The equine metabolic syndrome: Peripheral Cushing's syndrome

PJ Johnson - Veterinary Clinics: Equine Practice, 2002 - vetequine.theclinics.com
In recent years, there has been considerable interest in the association between the
development of obesity in mature horses and risk of laminitis [1]. Unlike the often cripplingly …

[HTML][HTML] Paradigm shifts in understanding equine laminitis

JC Patterson-Kane, NP Karikoski, CM McGowan - The Veterinary Journal, 2018 - Elsevier
Laminitis, one of the most debilitating conditions of all equids, is now known to be the result
of several systemic disease entities. This finding, together with other recent developments in …

ECEIM consensus statement on equine metabolic syndrome

AE Durham, N Frank, CM McGowan… - Journal of veterinary …, 2019 - Wiley Online Library
Equine metabolic syndrome (EMS) is a widely recognized collection of risk factors for
endocrinopathic laminitis. The most important of these risk factors is insulin dysregulation …

Equine laminitis: induced by 48 h hyperinsulinaemia in Standardbred horses

MA de Laat, CM McGowan, MN Sillence… - Equine veterinary …, 2010 - Wiley Online Library
Reasons for performing study: Hyperinsulinaemia is known to induce laminitis
experimentally in healthy ponies with no history of the condition. Horses are more insulin …

Prediction of incipient pasture‐associated laminitis from hyperinsulinaemia, hyperleptinaemia and generalised and localised obesity in a cohort of ponies

RA Carter, KH Treiber, RJ Geor… - Equine veterinary …, 2009 - Wiley Online Library
Reasons for performing study: The ability to predict ponies at increased risk of laminitic
episodes, when exposed to nutrient dense pasture, would facilitate management to avoid …

Obesity and diet affect glucose dynamics and insulin sensitivity in Thoroughbred geldings

RM Hoffman, RC Boston, D Stefanovski… - Journal of animal …, 2003 - academic.oup.com
Insulin resistance is considered a risk factor in obesity, laminitis, exertional rhabdomyolysis,
and osteochondrosis. The objective was to use the minimal model to estimate glucose …

Relationships among inflammatory cytokines, obesity, and insulin sensitivity in the horse,

MM Vick, AA Adams, BA Murphy… - Journal of animal …, 2007 - academic.oup.com
Recent studies associate obesity and insulin resistance in horses with development of
abnormal reproductive function and debilitating laminitis. The factors contributing to insulin …

Physical characteristics, blood hormone concentrations, and plasma lipid concentrations in obese horses with insulin resistance

N Frank, SB Elliott, LE Brandt… - Journal of the American …, 2006 - Am Vet Med Assoc
Objective—To compare obese horses with insulin resistance (IR) with nonobese horses and
determine whether blood resting glucose, insulin, leptin, and lipid concentrations differed …

Equine hyperinsulinemia: investigation of the enteroinsular axis during insulin dysregulation

MA de Laat, JM McGree… - American Journal of …, 2016 - journals.physiology.org
Compared with some other species, insulin dysregulation in equids is poorly understood.
However, hyperinsulinemia causes laminitis, a significant and often lethal disease affecting …

Breed differences in insulin sensitivity and insulinemic responses to oral glucose in horses and ponies of moderate body condition score

NJ Bamford, SJ Potter, PA Harris, SR Bailey - Domestic animal …, 2014 - Elsevier
Breed-related differences may occur in the innate insulin sensitivity (SI) of horses and
ponies, an important factor believed to be associated with the risk of laminitis. The aim of this …