Thoracic surgery faces many unique challenges that require innovative solutions. The
increase in utilization of minimally invasive practices, poor overall cancer survival and …

Diffuse optical tomography (DOT) is one of the emerging modalities for the non-invasive
imaging of thick biological tissues using near-infrared (NIR) light. This article reviews the …

Objective: Macroscopic optical tomography is a non-invasive method that can visualize the
3D distribution of intrinsic optical properties or exogenous fluorophores, making it highly …

Fluorescence guided surgery (FGS) is a developing field of surgical and oncologic research.
Practically, FGS has shown useful applications in urologic surgery, benign biliary surgery …

To develop an indocyanine green (ICG) tracer with slower clearance kinetics, we explored
ICG-encapsulating liposomes (Lip) in three different formulations: untargeted (Lip/ICG) …

Translation of fluorescence imaging using molecularly targeted imaging agents for real-time
assessment of surgical margins in the operating room requires a fast and reliable method to …

Purpose: The aim of this study is to determine if dynamic optical imaging could provide
comparable kinetic parameters to that of dynamic PET imaging by a near-infrared dye/64 Cu …

Spatial and temporal coregistration of nuclear and optical images can enable the fusion of
the information from these complementary molecular imaging modalities. A critical challenge …

Significance Rapid estimation of the depth and margins of fluorescence targets buried below
the tissue surface could improve upon current image-guided surgery techniques for tumor …

Purpose Ischemia-related processes associated with the generation of inflammatory
molecules such as reactive oxygen species (ROS) are difficult to detect at the acute stage …