IL‐2 receptor (IL‐2R) signalling is critical for normal lymphocyte proliferation, but its role in
cervical cancer is not fully understood. The receptor is composed of three chains: IL‐2α, IL …

With the wide use of biomarkers to enable critical drug-development decisions, there is a
growing concern from scientific community on the need for a 'standardized process' for …

Oxidative stress plays a critical role in numerous diseases. Therefore, the pursuit of
compounds with antioxidant activity remains critical. Green barley young leaves aqueous …

Natural killer (NK) cells are suitable targets for cancer immunotherapy owing to their potent
cytotoxic activity. To maximize the therapeutic efficacy of cancer immunotherapy, adjuvants …

The pleiotropic cytokine interleukin 2 (IL2) disrupts the blood-brain barrier and alters brain
microcirculation, underlying vascular leak syndrome that complicates cancer …

Regulation of intracellular signaling pathways in lymphocytes is critical for cell homeostasis
and immune response. Interleukin-2 (IL-2), a key regulator of lymphocytes, signals following …

Camelina sativa is an alternative protein source (with a specific amino acid profile) rich also
in bioactive compounds (such as polyunsaturated fatty acids and antioxidants), which have …

Angiogenesis, neovascularization, and vascular remodeling are highly dynamic processes,
where endothelial cell–cell adhesion within the vessel wall controls a range of physiological …

Background: A medical need exists for successfully treating patients afflicted with leukemia
and especially those that relapse and ultimately become refractory to front line …

Janus tyrosine kinase 3 (JAK3) is primarily expressed in immune cells and is needed for
signaling by the common gamma chain (γc) family of cytokines. Abnormal JAK3 signal …