Worms' antimicrobial peptides

R Bruno, M Maresca, S Canaan, JF Cavalier… - Marine drugs, 2019 - mdpi.com
Antimicrobial peptides (AMPs) are natural antibiotics produced by all living organisms. In
metazoans, they act as host defense factors by eliminating microbial pathogens. But they …

Strategies for recombinant production of antimicrobial peptides with pharmacological potential

KB Sampaio de Oliveira, ML Leite… - Expert review of …, 2020 - Taylor & Francis
Introduction The need to develop new drugs for the control of pathogenic microorganisms
has redoubled efforts to prospect for antimicrobial peptides (AMPs) from natural sources and …

Expression, Purification, and Antibacterial Activity of Bovine Lactoferrampin–Lactoferricin in Pichia pastoris

XS Tang, ZR Tang, SP Wang, ZM Feng, D Zhou… - Applied biochemistry …, 2012 - Springer
Bovine lactoferrampin (LFA) and bovine lactoferricin (LFC) are two antimicrobial peptides
located in the N 1 domain of bovine lactoferrin. The bactericidal activity of the fused peptide …

A novel alkaline serine protease with fibrinolytic activity from the polychaete, Neanthes japonica

S Wang, Z Deng, Q Li, X Ge, Q Bo, J Liu, J Cui… - … and Physiology Part B …, 2011 - Elsevier
A new protease named NJP with fibrinolytic activity was isolated from Neanthes japonica
(Izuka), by a combination of ammonium sulfate fractionation, hydrophobic chromatography …

Mechanisms of intestinal injury in polychaete Perinereis aibuhitensis caused by low-concentration fluorene pollution: microbiome and metabonomic analyses

T Teng, Y Yang, H Li, J Song, J Ren, F Liu - Journal of Hazardous Materials, 2024 - Elsevier
The polychaete Perinereis aibuhitensis is used for bioremediation; however, its ability to
remove fluorene, a common environmental pollutant, from sediments remains unclear …

Efficient biosynthesis of a Cecropin A-melittin mutant in Bacillus subtilis WB700

S Ji, W Li, AR Baloch, M Wang, H Li, B Cao, H Zhang - Scientific reports, 2017 - nature.com
The efficient production of antimicrobial peptides (AMPs) for clinical applications has
attracted the attention of the scientific community. To develop a novel microbial cell factory …

Characterization of bioactive recombinant antimicrobial peptide parasin I fused with human lysozyme expressed in the yeast Pichia pastoris system

H Zhao, J Tang, L Cao, G Jia, D Long, G Liu… - Enzyme and microbial …, 2015 - Elsevier
Parasin I (PI) is a 19 amino acid peptide with potent antimicrobial activities against a broad
spectrum of microorganisms and is a good candidate for development as a novel …

The marine ecosystem as a source of antibiotics

Y López, V Cepas, SM Soto - Grand challenges in marine biotechnology, 2018 - Springer
There has been a decline in the development of antibiotics over the past few decades.
Following the discovery of penicillin in 1928, 15–20 new antibiotics were developed each …

Expression in Pichia Pastoris and biological activity of Avian β-defensin 6 and its mutant peptide without cysteines

Y Cao, Q Ma, A Shan, N Dong - Protein And Peptide Letters, 2012 - ingentaconnect.com
Avian β-defensin 6 (AvBD-6) is an antimicrobial peptide that plays significant roles in the
innate immunity of chickens. To explore the effects of disulfide bonds on antimicrobial …

Anti-inflammatory and antioxidant effects of clam worm extract treated with peptidoglycan

S Kim, M Sapkota, M Yang, L Li… - Korean Journal of …, 2017 - koreascience.kr
Peptidoglycan in inserts and mammals is well known to improve biological functions in the
host's immune system. However, it is unclear how Peptidoglycan exerted its anti …