Although the development of effective viral vectors put gene therapy on the road to
commercialization, nonviral vectors show promise for practical use because of their relative …

Long-term exposure to peroxisome proliferator-activated receptor γ (PPARγ) agonists such
as rosiglitazone induces browning of rodent and human adipocytes; however, the …

Adipose tissue-derived stem cells (ADSCs) have shown potential for the treatment of nerve
injuries. Most previous efforts have aimed at stimulating regeneration by using neural …

Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis and essential to
maintain the continuous production of spermatozoa after the onset of puberty in the male …

Bone regeneration achieved using mesenchymal stem cells (MSCs) and nonviral gene
therapy holds great promise for patients with fractures seemingly unable to heal. Previously …

Multiple factors alter intervertebral disc volume, structure, shape, composition, and
biomechanical properties, often leading to low back pain. Spinal fusion is frequently …

Mesenchymal stem cells (MSCs) have an extensive migratory capacity for gliomas, which is
comparable to that of neural stem cells. Among the various types of MSCs, human adipose …

Technologies designed to allow manipulation and modification of human embryonic stem
(hES) cells are numerous and vary in the complexity of their methods, efficiency, reliability …

Mesenchymal stem cells (MSCs) hold tremendous potential for therapeutic use in stem cell-
based gene therapy. Ex vivo genetic modification of MSCs with beneficial genes of interest …

Human degenerative cartilage has low regenerative potential. Chondrocyte transplantation
offers a promising strategy for cartilage treatment and regeneration. Currently …