[HTML][HTML] Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes
K Kistamás, A Müller, S Muenthaisong… - Journal of Molecular …, 2023 - Elsevier
Cardiovascular diseases are the leading cause of death worldwide. Several strategies–
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …
The Novel Long QT Syndrome Type 2-associated F129I Mutation in the KCNH2 Gene Significantly Affects IKr Through the hERG1 Homomeric and Heteromeric …
L Feng, K Ma, X Li, N Liu, D Long, C Ma - Cardiology Discovery, 2024 - journals.lww.com
Objective: The long QT syndrome type 2 is caused by the loss-of-function mutations in the
KCNH2 gene, which encodes hERG1, the voltage-gated potassium channel. The hERG1 …
KCNH2 gene, which encodes hERG1, the voltage-gated potassium channel. The hERG1 …
The hERG1 PAS Domain: An Anti-arrhythmic Drug Target and Master Regulator of IKr
C Ukachukwu - 2023 - deepblue.lib.umich.edu
The hERG1 potassium channel conducts the cardiac repolarizing current IKr. It is one of the
first currents to appear in the heart and its disruption is associated with cardiac disorders …
first currents to appear in the heart and its disruption is associated with cardiac disorders …