Chronic inflammation in FMF: markers, risk factors, outcomes and therapy

I Ben-Zvi, A Livneh - Nature Reviews Rheumatology, 2011 - nature.com
Familial Mediterranean fever (FMF) is the most common of the hereditary periodic fever
syndromes. Although the typical clinical course of FMF is characterized by bouts of painful …

Autoimmunity vs autoinflammation in Behcet's disease: do we oversimplify a complex disorder?

H Direskeneli - Rheumatology, 2006 - academic.oup.com
Behcet's disease (BD) is a systemic inflammatory disorder with a diverse spectrum of clinical
manifestations including mucocutaneous, ocular, vascular, gastrointestinal, musculoskeletal …

Peripheral T cell populations are differentially affected in familial Mediterranean fever, chronic granulomatous disease, and gout

B Al, M Bruno, RJ Röring, SJ Moorlag, TK Suen… - Journal of Clinical …, 2023 - Springer
Both innate errors of immunity, such as familial Mediterranean fever (FMF) and chronic
granulomatous disease (CGD), and the common inflammatory disease gout are …

Mean platelet volume as a potential predictor of proteinuria and amyloidosis in familial Mediterranean fever

H Sakallı, Ö Kal - Clinical rheumatology, 2013 - Springer
This study aims to compare the mean platelet volume (MPV) levels in children and adults
diagnosed with familial Mediterranean fever (FMF) during attack-free periods in order to find …

Cytokine profile of Armenian patients with familial Mediterranean fever

GP Manukyan, KA Ghazaryan, ZA Ktsoyan… - Clinical …, 2008 - Elsevier
OBJECTIVES: Despite the well-defined genetics of FMF, limited information is available
regarding the regulation of inflammation by cytokines. DESIGN AND METHODS: The levels …

[HTML][HTML] ABO blood groups and rheumatic diseases

S Çildağ, Y Kara, T Şentürk - European journal of rheumatology, 2017 - ncbi.nlm.nih.gov
Objective Various genetic and environmental risk factors have been shown to be associated
with the incidence of rheumatic diseases. However, the pathogenesis of rheumatic diseases …

Intima–media thickening in patients with familial Mediterranean fever

S Ugurlu, E Seyahi, F Cetinkaya, F Ozbakır… - …, 2009 - academic.oup.com
Objective. The aim of this study was to assess the frequency of atherosclerotic plaques and
intima–media thickness (IMT) in patients with FMF and suitable controls. Methods. We …

Ex vivo PBMC cytokine profile in familial Mediterranean fever patients: Involvement of IL-1β, IL-1α and Th17-associated cytokines and decrease of Th1 and Th2 …

JN Ibrahim, R Jounblat, A Delwail, J Abou-Ghoch… - Cytokine, 2014 - Elsevier
In order to clarify the inflammatory mechanism underlying familial Mediterranean fever
(FMF), we aimed to evaluate the ex vivo cytokine profile of FMF patients during acute attacks …

Serum proinflammatory cytokines directing T helper 1 polarization in patients with familial Mediterranean fever

I Simsek, S Pay, A Pekel, A Dinc, U Musabak… - Rheumatology …, 2007 - Springer
Th1 type polarization has been implicated in the pathogenesis of familial Mediterranean
fever (FMF). Interleukin-12 (IL-12) and IL-10 are proinflammatory cytokines, which play …

Prevalence and significance of MEFV gene mutations in a cohort of patients with rheumatoid arthritis

SS Koca, EO Etem, B Isik, H Yuce, M Ozgen, MS Dag… - Joint Bone Spine, 2010 - Elsevier
OBJECTIVES: Pyrin/marenostrin, an inhibitory regulator of inflammation, is encoded by
MEditerranean FeVer (MEFV) gene. Mutations of this gene are the cause of familial …