The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease

G Feng, L Valenti, VWS Wong, YM Fouad… - Nature Reviews …, 2024 - nature.com
Recompensation has gained increasing attention in the field of cirrhosis, particularly in
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …

Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update 2021

AF Peery, SD Crockett, CC Murphy, ET Jensen, HP Kim… - Gastroenterology, 2022 - Elsevier
Background & Aims Gastrointestinal diseases account for considerable health care use and
expenditures. We estimated the annual burden, costs, and research funding associated with …

[HTML][HTML] Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation

LE Leard, AM Holm, M Valapour, AR Glanville… - The Journal of Heart and …, 2021 - Elsevier
Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral …

Epidemiology and risk-stratification of NAFLD-associated HCC

GN Ioannou - Journal of hepatology, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …

Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

MAFLD: A multisystem disease

RM Pipitone, C Ciccioli, G Infantino… - Therapeutic …, 2023 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

[HTML][HTML] Liver transplantation 2023: status report, current and future challenges

NA Terrault, C Francoz, M Berenguer… - Clinical …, 2023 - Elsevier
Liver transplantation offers live-saving therapy for patients with complications of cirrhosis
and stage T2 hepatocellular carcinoma. The demand for organs far outstrips the supply, and …

Progress towards elimination goals for viral hepatitis

AL Cox, MH El-Sayed, JH Kao, JV Lazarus… - Nature reviews …, 2020 - nature.com
The global burden of viral hepatitis is substantial; in terms of mortality, hepatitis B virus and
hepatitis C virus infections are on a par with HIV, malaria and tuberculosis, among the top …

Liver transplantation in hepatocellular carcinoma after tumour downstaging (XXL): a randomised, controlled, phase 2b/3 trial

V Mazzaferro, D Citterio, S Bhoori, M Bongini… - The Lancet …, 2020 - thelancet.com
Background Indications for liver transplantation for hepatocellular carcinoma are evolving
and so-called expanded criteria remain debated. Locoregional therapies are able to …