Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

Air pollution is a rising public health issue worldwide. Cumulative epidemiological and
experimental studies have shown that exposure to air pollution such as particulate matter …

Myocardial fibrosis is recognized as a key pathological process in the development of
cardiac disease and a target for future therapeutics. Despite this recognition, the assessment …

Background Reendothelialisation is the natural pathway that inhibits neointimal hyperplasia
and in-stent restenosis. Circulating endothelial progenitor cells (EPCs) derived from bone …

Tissue imaging in 3D using visible light is limited and various clearing techniques were
developed to increase imaging depth, but none provides universal solution for all tissues at …

Rationale: Remodeling of the vessel wall and the formation of vascular networks are
dynamic processes that occur during mammalian embryonic development and in adulthood …

Biomechanical forces intimately contribute to cardiac morphogenesis. However, volumetric
imaging to investigate the cardiac mechanics with high temporal and spatial resolution …

The heart is a complex multi-scale system composed of components integrated at the
subcellular, cellular, tissue and organ levels. The myocytes, the contractile elements of the …

Zebrafish is an intriguing model organism known for its remarkable cardiac regeneration
capacity. Studying the contracting heart in vivo is essential for gaining insights into structural …

We report a novel fusion of microfluidics and light-field microscopy, to achieve high-speed
4D (space+ time) imaging of moving C. elegans on a chip. Our approach combines …