Fingerprinting and profiling in metabolomics of biosamples

V Ghini, G Meoni, A Vignoli, F Di Cesare… - Progress in Nuclear …, 2023 - Elsevier
This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

[HTML][HTML] Magnetic resonance spectroscopy—revisiting the biochemical and molecular milieu of brain tumors

A Verma, I Kumar, N Verma, P Aggarwal, R Ojha - BBA clinical, 2016 - Elsevier
Background Magnetic resonance spectroscopy (MRS) is an established tool for in-vivo
evaluation of the biochemical basis of human diseases. On one hand, such lucid depiction …

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

O Beckonert, M Coen, HC Keun, Y Wang… - Nature protocols, 2010 - nature.com
Metabolic profiling, metabolomic and metabonomic studies require robust study protocols for
any large-scale comparisons and evaluations. Detailed methods for solution-state NMR …

Metabolic Profiling of Human Lung Cancer Tissue by 1H High Resolution Magic Angle Spinning (HRMAS) NMR Spectroscopy

CM Rocha, AS Barros, AM Gil… - Journal of proteome …, 2010 - ACS Publications
This work aims at characterizing the metabolic profile of human lung cancer, to gain new
insights into tumor metabolism and to identify possible biomarkers with potential diagnostic …

Metabolic Profiling of Lung Granuloma in Mycobacterium tuberculosis Infected Guinea Pigs: Ex vivo 1H Magic Angle Spinning NMR Studies

BS Somashekar, AG Amin, CD Rithner… - Journal of proteome …, 2011 - ACS Publications
A crucial and distinctive feature of tuberculosis infection is that Mycobacterium tuberculosis
(Mtb) resides in granulomatous lesion at various stages of disease development and …

Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues

BS Somashekar, P Kamarajan, T Danciu… - Journal of proteome …, 2011 - ACS Publications
High-resolution magic-angle spinning (HR-MAS) proton NMR spectroscopy is used to
explore the metabolic signatures of head and neck squamous cell carcinoma (HNSCC) …

Advanced imaging of intracranial meningiomas

B Tamrazi, MS Shiroishi… - Neurosurgery Clinics, 2016 - neurosurgery.theclinics.com
Background Meningiomas arise from the arachnoid meningothelial cells. Intracranially, they
are extra-axial masses that are typically T1 isointense to slightly hypointense and T2 …

HR MAS MR spectroscopy in metabolic characterization of cancer

S Moestue, B Sitter, T Frost Bathen… - Current topics in …, 2011 - ingentaconnect.com
One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order
to cope with increased requirement for building blocks and energy, cancer cells develop …

High-resolution magic angle spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer

B Sitter, TF Bathen, MB Tessem… - Progress in nuclear …, 2009 - Elsevier
Cancer is a disease with high prevalence in western and industrialized countries. The
incidence of cancer has been increasing, while mortality has either been stable or …

Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers

AJ Wright, GA Fellows, JR Griffiths, M Wilson, BA Bell… - Molecular cancer, 2010 - Springer
Background High-resolution magic angle spinning (HRMAS) NMR spectroscopy allows
detailed metabolic analysis of whole biopsy samples for investigating tumour biology and …