mRNA stability in mammalian cells

J Ross - Microbiological reviews, 1995 - Am Soc Microbiol
This review concerns how cytoplasmic mRNA half-lives are regulated and how mRNA decay
rates influence gene expression. mRNA stability influences gene expression in virtually all …

MRNA stability and the control of gene expression: implications for human disease

EM Hollams, KM Giles, AM Thomson… - Neurochemical …, 2002 - Springer
Regulation of gene expression is essential for the homeostasis of an organism, playing a
pivotal role in cellular proliferation, differentiation, and response to specific stimuli. Multiple …

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

W Zhang, BJ Wagner, K Ehrenman… - … and cellular biology, 1993 - Am Soc Microbiol
The degradation of some proto-oncogene and lymphokine mRNAs is controlled in part by an
AU-rich element (ARE) in the 3′ untranslated region. It was shown previously (G. Brewer …

Stem-loop binding protein, the protein that binds the 3′ end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms

ML Whitfield, LX Zheng, A Baldwin, T Ohta… - … and cellular biology, 2000 - Taylor & Francis
The expression of the replication-dependent histone mRNAs is tightly regulated during the
cell cycle. As cells progress from G1 to S phase, histone mRNA levels increase 35-fold, and …

Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3'UTR structures

AM Ward, K Bidet, A Yinglin, SG Ler, K Hogue… - RNA biology, 2011 - Taylor & Francis
Dengue virus (DENV) is a rapidly re-emerging flavivirus that causes dengue fever (DF),
dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), diseases for which …

The protein that binds the 3'end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.

ZF Wang, ML Whitfield, TC Ingledue… - Genes & …, 1996 - genesdev.cshlp.org
Replication-dependent histone mRNAs are not polyadenylated but end in a conserved 26-
nucleotide structure that contains a stem-loop. Much of the cell cycle regulation of histone …

Formation of the 3′ end of histone mRNA

Z Dominski, WF Marzluff - Gene, 1999 - Elsevier
All metazoan messenger RNAs, with the exception of the replication-dependent histone
mRNAs, terminate at the 3′ end with a poly (A) tail. Replication-dependent histone mRNAs …

Pbp1p, a Factor Interacting withSaccharomyces cerevisiae Poly(A)-Binding Protein, Regulates Polyadenylation

DA Mangus, N Amrani, A Jacobson - Molecular and cellular biology, 1998 - Taylor & Francis
The poly (A) tail of an mRNA is believed to influence the initiation of translation, and the rate
at which the poly (A) tail is removed is thought to determine how fast an mRNA is degraded …

High-throughput characterization of protein–RNA interactions

KB Cook, TR Hughes, QD Morris - Briefings in functional …, 2015 - academic.oup.com
RNA-binding proteins (RBPs) are important regulators of eukaryotic gene expression.
Genomes typically encode dozens to hundreds of proteins containing RNA-binding …

The stem-loop binding protein is required for efficient translation of histone mRNA in vivo and in vitro

R Sànchez, WF Marzluff - Molecular and cellular biology, 2002 - Taylor & Francis
Metazoan replication-dependent histone mRNAs end in a conserved stem-loop rather than
in the poly (A) tail found on all other mRNAs. The 3′ end of histone mRNA binds a single …