Methods to functionalize arenes and heteroarenes in a site-selective manner are highly
sought after for rapidly constructing value-added molecules of medicinal, agrochemical, and …

This tutorial review focuses on several practical synthetic transformations utilising palladium
catalysis that facilitate the synthesis of functionalised unsaturated heterocycles in a …

Covering the fundamentals of heterocyclic reactivity and synthesis, this book teaches the
subject in a way that is understandable to graduate students. Recognizing the level at which …

Site-selective dihalogenated heteroarene cross-coupling with organometallic reagents
usually occurs at the halogen proximal to the heteroatom, enabled by intrinsic relative …

Sequential cross-coupling on multihalogenated heterocycles is a particularly attractive
strategy for the divergent synthesis of polysubstituted heterocycles, but the factors that …

Four‐membered carbocycles are important structural motifs found in several natural
products and drugs. Amongst those, cyclobutenes are attractive intermediates because the …

Electrochemical techniques have long been heralded for their innate sustainability as
efficient methods to achieve redox reactions. Carbonyl desaturation, as a fundamental …

While chemoselectivities in Pd0‐catalyzed coupling reactions are frequently non‐intuitive
and a result of a complex interplay of ligand/catalyst, substrate, and reaction conditions, we …

Selectivity of the palladium-catalyzed cross-coupling reactions of heterocycles bearing
multiple identical halogens is mainly determined by the relative ease of oxidative addition …

Use of attractive noncovalent interactions between ligand and substrate is an emerging
strategy for controlling positional selectivity. A key question relates to whether fine control on …