Platelet “first responders” in wound response, cancer, and metastasis
DG Menter, S Kopetz, E Hawk, AK Sood… - Cancer and Metastasis …, 2017 - Springer
Platelets serve as “first responders” during normal wounding and homeostasis. Arising from
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …
[HTML][HTML] Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective
DG Menter, V Afshar-Kharghan, JP Shen… - Cancer and Metastasis …, 2022 - Springer
We have established considerable expertise in studying the role of platelets in cancer
biology. From this expertise, we were keen to recognize the numerous venous-, arterial …
biology. From this expertise, we were keen to recognize the numerous venous-, arterial …
Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device
Circulating tumor cells (CTC) in the peripheral blood could provide important information for
diagnosis of cancer metastasis and monitoring treatment progress. However, CTC are …
diagnosis of cancer metastasis and monitoring treatment progress. However, CTC are …
[HTML][HTML] The provocative roles of platelets in liver disease and cancer
P Kanikarla Marie, NW Fowlkes… - Frontiers in …, 2021 - frontiersin.org
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
[HTML][HTML] The provocative roles of platelets in liver disease and cancer
PK Marie, NW Fowlkes, V Afshar-Kharghan… - Frontiers in …, 2021 - ncbi.nlm.nih.gov
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
Bioactive lipid metabolism in platelet “first responder” and cancer biology
P Kanikarla-Marie, S Kopetz, ET Hawk… - Cancer and Metastasis …, 2018 - Springer
Platelets can serve as “first responders” in cancer and metastasis. This is partly due to
bioactive lipid metabolism that drives both platelet and cancer biology. The two primary …
bioactive lipid metabolism that drives both platelet and cancer biology. The two primary …
Facile compliance-based pump for blood physiometer
YJ Kang - Physics of Fluids, 2024 - pubs.aip.org
The biomechanical properties of blood are considered promising label-free biomarkers for
early disease detection. Disposable pumps have been suggested as replacements for bulky …
early disease detection. Disposable pumps have been suggested as replacements for bulky …
Microfluidic fabrication of biocompatible poly (N-vinylcaprolactam)-based microcarriers for modulated thermo-responsive drug release
Various thermo-responsive polymers have been developed for controlled drug delivery
upon the local application of external heat. The development of thermo-responsive polymers …
upon the local application of external heat. The development of thermo-responsive polymers …
Assaying the efficacy of dual-antiplatelet therapy: use of a controlled-shear-rate microfluidic device with a well-defined collagen surface to track dynamic platelet …
We report the development and demonstration of an assay that distinguishes the
pharmacological effects of two widely used antiplatelet therapies, aspirin (COX-1 inhibitor) …
pharmacological effects of two widely used antiplatelet therapies, aspirin (COX-1 inhibitor) …
Successful kidney transplantation normalizes platelet function
Background Uraemic platelet dysfunction is not completely understood, in part due to non-
physiological platelet function assays. We have developed a physiological flow-based assay …
physiological platelet function assays. We have developed a physiological flow-based assay …