Human papillomavirus molecular biology and disease association

J Doorbar, N Egawa, H Griffin… - Reviews in medical …, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

The biology and life-cycle of human papillomaviruses

J Doorbar, W Quint, L Banks, IG Bravo, M Stoler… - Vaccine, 2012 - Elsevier
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …

Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing

CHL Kürten, A Kulkarni, AR Cillo, PM Santos… - Nature …, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations
between stromal, epithelial, and immune cells within the tumor microenvironment (TME). To …

Parity as a cofactor for high-grade cervical disease among women with persistent human papillomavirus infection: a 13-year follow-up

KE Jensen, S Schmiedel, B Norrild… - British journal of …, 2013 - nature.com
Background: Several environmental factors have been associated with increased risks for
cervical cancer. We examined whether reproductive history, contraceptive use, or sexual …

Estrogenic terpenes and terpenoids: Pathways, functions and applications

R Kiyama - European Journal of Pharmacology, 2017 - Elsevier
Terpenes are made of the isoprene unit (C 5), and along with their derivatives, terpenoids,
they are widely distributed in plants as active ingredients involved in anti-inflammation, anti …

HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head …

R Marullo, E Werner, H Zhang, GZ Chen… - …, 2015 - academic.oup.com
Human papillomavirus (HPV) is the causative agent of a subgroup of head and neck cancer
characterized by an intrinsic radiosensitivity. HPV initiates cellular transformation through …

[HTML][HTML] The role of human papillomaviruses in cancer progression

P Tulay, N Serakinci - Journal of Cancer Metastasis and Treatment, 2016 - oaepublish.com
The importance of human papillomavirus (HPV) infection and its role in the progress of
cancer have been widely evaluated. The understanding of HPV association with certain …

A review of dietary prevention of human papillomavirus-related infection of the cervix and cervical intraepithelial neoplasia

HJ Chih, AH Lee, L Colville, CW Binns, D Xu - Nutrition and cancer, 2013 - Taylor & Francis
The natural history of cervical cancer suggests that prevention can be achieved by
modification of the host's immune system through a nutrient-mediated program. This study …

Unraveling Immunological Dynamics: HPV Infection in Women—Insights from Pregnancy

CE Condrat, D Cretoiu, VE Radoi, DM Mihele… - Viruses, 2023 - mdpi.com
During pregnancy, hormonal and immune adaptations are vital for supporting the genetically
distinct fetus during elevated infection risks. The global prevalence of HPV necessitates its …

[HTML][HTML] Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue

EM Cortés-Malagón, J Bonilla-Delgado, J Díaz-Chávez… - Virology, 2013 - Elsevier
The HPV16 E7 oncoprotein and 17β-estradiol are important factors for the induction of
premalignant lesions and cervical cancer. The study of these factors is crucial for a better …