Insoluble polysaccharides can be degraded by a set of hydrolytic enzymes formed by
catalytic modules appended to one or more non-catalytic carbohydrate-binding modules …

Computational aided drug design (CADD) is presently a key component in the process of
drug discovery and development as it offers great promise to drastically reduce cost and …

Saturation transfer difference (STD) NMR has emerged as one of the most popular ligand-
based NMR techniques for the study of protein− ligand interactions. The success of this …

Neurons are extremely energy demanding cells and highly dependent on the mitochondrial
oxidative phosphorylation (OXPHOS) system. Mitochondria generate the energetic potential …

Introduction: In the recent decades, the interest on glycosidases has dramatically increased,
mainly because these enzymes play a key role in many biological processes. The …

Glucans are polymers of d-glucose with differing linkages in linear or branched sequences.
They are constituents of microbial and plant cell-walls and involved in important bio …

In the recent decades, the interest on glycosidases has dramatically increased, mainly
because these enzymes play a vital role in many biological processes. Based on the …

This study describes the interaction between crystalline cellulose and the direct dye Congo
red (CR) using molecular dynamics simulations. A model of a microfibril corner of cellulose …

Knowledge of the three-dimensional structures of the carbohydrate molecules is
indispensable for a full understanding of the molecular processes in which carbohydrates …

Carbohydrate binding modules (CBMs) are non-catalytic domains within larger multidomain
polypeptides. The CelH from Ruminoclostridium (Clostridium) thermocellum contains a …