Computed tomographic coronary angiography–derived plaque characteristics predict major adverse cardiovascular events: a systematic review and meta-analysis

N Nerlekar, FJ Ha, C Cheshire, H Rashid… - Circulation …, 2018 - Am Heart Assoc
Background—Computed tomographic coronary angiography is a noninvasive imaging
modality that permits identification and characterization of coronary plaques. Despite …

High wall shear stress and high-risk plaque: an emerging concept

P Eshtehardi, AJ Brown, A Bhargava… - The international journal …, 2017 - Springer
In recent years, there has been a significant effort to identify high-risk plaques in vivo prior to
acute events. While number of imaging modalities have been developed to identify …

Identification of high-risk plaques destined to cause acute coronary syndrome using coronary computed tomographic angiography and computational fluid dynamics

JM Lee, G Choi, BK Koo, D Hwang, J Park… - Cardiovascular …, 2019 - jacc.org
Objectives The authors investigated the utility of noninvasive hemodynamic assessment in
the identification of high-risk plaques that caused subsequent acute coronary syndrome …

High coronary shear stress in patients with coronary artery disease predicts myocardial infarction

A Kumar, EW Thompson, A Lefieux, DS Molony… - Journal of the American …, 2018 - jacc.org
Background: Coronary lesions with low fractional flow reserve (FFR) that are treated
medically are associated with higher revascularization rates. High wall shear stress (WSS) …

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap …

DM Leistner, N Kränkel, D Meteva… - European Heart …, 2020 - academic.oup.com
Aims Acute coronary syndromes with intact fibrous cap (IFC-ACS), ie caused by coronary
plaque erosion, account for approximately one-third of ACS. However, the underlying …

Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition

C Costopoulos, LH Timmins, Y Huang… - European heart …, 2019 - academic.oup.com
Aims The focal distribution of atherosclerotic plaques suggests that local biomechanical
factors may influence plaque development. Methods and results We studied 40 patients at …

[HTML][HTML] Calcifications in atherosclerotic plaques and impact on plaque biomechanics

HE Barrett, K Van der Heiden, E Farrell… - Journal of …, 2019 - Elsevier
The catastrophic mechanical rupture of an atherosclerotic plaque is the underlying cause of
the majority of cardiovascular events. The infestation of vascular calcification in the plaques …

Interactions between morphological plaque characteristics and coronary physiology: from pathophysiological basis to clinical implications

S Yang, BK Koo, J Narula - Cardiovascular Imaging, 2022 - jacc.org
High-risk coronary plaque refers to a distinct set of plaque characteristics prone to future
coronary events. Coronary physiology represents a group of indexes reflective of the local …

The MRI enhancement ratio and plaque steepness may be more accurate for predicting recurrent ischemic cerebrovascular events in patients with intracranial …

D Yang, J Liu, W Yao, K Huang, C Zhou, J Bi… - European …, 2022 - Springer
Objectives To assess the complementary value of high-resolution multi-contrast MRI (hrMRI)
in identifying symptomatic patients with intracranial atherosclerosis (ICAS) who are likely to …

[HTML][HTML] Current and future applications of artificial intelligence in coronary artery disease

N Gautam, P Saluja, A Malkawi, MG Rabbat… - Healthcare, 2022 - mdpi.com
Cardiovascular diseases (CVDs) carry significant morbidity and mortality and are associated
with substantial economic burden on healthcare systems around the world. Coronary artery …