The gene expression profile of the aging process was analyzed in skeletal muscle of mice.
Use of high-density oligonucleotide arrays representing 6347 genes revealed that aging …

It is believed that intracellular and extracellular advanced glycation (AGEs) or lipoxidation
end products (ALEs), together with dysregulated glucose and lipid metabolism, are …

Investigating the molecular mechanisms underlying sarcopenia in humans with the use of
microarrays has been complicated by low sample size and the variability inherent in human …

Although the molecular mechanism of aging is unknown, a progressive increase with age in
the concentration of damaged macromolecules, especially proteins, is likely to play a central …

Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to
clinical application, analyzing the fundamental cellular changes which underlie human age …

The hippocampus, an area with abundant glucocorticoid receptors, continues to be the focus
of research on effects of glucocorticoids on the aging brain. Based on recent studies, the …

To gain a better understanding of the potential role of altered gene expression in the
diminished muscle function in old age, we performed a broad search for transcripts …

Although there appear to be several influences, which contribute to the ageing of mammals,
the role of DNA appears to be pivotal. There is increasing evidence that oxidative damage is …

Aged rats display a broad range of behavioral performance in spatial learning. The aim of
this study was to identify candidate genes that are associated with learning and memory …

Because of possible side effects of herbal medicines containing ephedrine and guarana-
derived caffeine, including increased risk of stroke, myocardial infarction, and sudden death …