[HTML][HTML] The role of wastewater treatment plants in dissemination of antibiotic resistance: source, measurement, removal and risk assessment

K Drane, M Sheehan, A Whelan, E Ariel, R Kinobe - Antibiotics, 2024 - mdpi.com
Antibiotic Resistance Genes (ARGs) are contaminants of emerging concern with marked
potential to impact public and environmental health. This review focusses on factors that …

Unleashing the power of polymeric nanoparticles—Creative triumph against antibiotic resistance: A review

AA Roy, S Mutalik, N Dhas - International Journal of Biological …, 2024 - Elsevier
Antibiotic resistance (ABR) poses a universal concern owing to the widespread use of
antibiotics in various sectors. Nanotechnology emerges as a promising solution to combat …

Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics

M Venkatesan, M Fruci, LA Verellen, T Skarina… - Nature …, 2023 - nature.com
The sulfonamides (sulfas) are the oldest class of antibacterial drugs and inhibit the bacterial
dihydropteroate synthase (DHPS, encoded by folP), through chemical mimicry of its co …

Toward a treatment of antibacterial and antifungal infections: Design, synthesis and in vitro activity of novel arylhydrazothiazolylsulfonamides analogues and their …

IMM Othman, MH Mahross, MAM Gad-Elkareem… - Journal of Molecular …, 2021 - Elsevier
To find out effective new antibacterial agents, a series of novel aryl-hydrazothiazolyl-
sulfonamide derivatives 3a-e were synthesized and well characterized by analytical and …

Sulfamethoxazole enhances specific enzymatic activities under aerobic heterotrophic conditions: a metaproteomic approach

DM Kennes-Veiga, A Trueba-Santiso… - Environmental …, 2022 - ACS Publications
The growing concern about antibiotic-resistant microorganisms has focused on the sludge
from wastewater treatment plants (WWTPs) as a potential hotspot for their development and …

Comparative Genomic Analysis of Staphylococcus haemolyticus Reveals Key to Hospital Adaptation and Pathogenicity

M Pain, E Hjerde, C Klingenberg… - Frontiers in …, 2019 - frontiersin.org
Staphylococcus haemolyticus is a skin commensal gaining increased attention as an
emerging pathogen of nosocomial infections. However, knowledge about the transition from …

Porphyromonas gingivalis: where do we stand in our battle against this oral pathogen?

KC Howard, OA Gonzalez… - RSC Medicinal …, 2021 - pubs.rsc.org
Periodontal diseases, such as gingivitis and periodontitis, are inflammatory diseases
triggered by pathogenic bacteria that lead to damage of the soft tissue and bone supporting …

Antimicrobial activity and molecular docking screening of bioactive components of Antirrhinum majus (snapdragon) aerial parts

FG Saqallah, WM Hamed, WH Talib, R Dianita… - Heliyon, 2022 - cell.com
Abstract Background Antirrhinum majus (Snapdragon) is a perennial Mediterranean-native
plant that is commonly used for mass display. Few reports acknowledged the traditional use …

Exploration into the origins and mobilization of di-hydrofolate reductase genes and the emergence of clinical resistance to trimethoprim

M Sánchez-Osuna, P Cortés… - Microbial …, 2020 - microbiologyresearch.org
Trimethoprim is a synthetic antibacterial agent that targets folate biosynthesis by
competitively binding to the di-hydrofolate reductase enzyme (DHFR). Trimethoprim is often …

Development of a dihydropteroate synthase-based fluorescence polarization assay for detection of sulfonamides and studying its recognition mechanism

T He, J Liu, JP Wang - Journal of Agricultural and Food Chemistry, 2021 - ACS Publications
In this study, the dihydropteroate synthase of Staphylococcus aureus was obtained, and its
recognition mechanisms for 31 sulfonamide drugs were studied. Results showed that their …