Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

Pathogenic potentials of the gastric pathogen, Helicobacter pylori, have been proposed,
evaluated, and confirmed by many laboratories for nearly 4 decades since its serendipitous …

The development of sequencing technology has expanded our knowledge of the human
gastric microbiome, which is now known to play a critical role in the maintenance of …

There are numerous ways that endocytic cargo molecules may be internalized from the
surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of …

Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

The plasma membrane represents a physical inelastic barrier with a given area that adheres
to the underlying cytoskeleton. The tension in the membrane physically affects cell functions …

The VacA toxin secreted by Helicobacter pylori enhances the ability of the bacteria to
colonize the stomach and contributes to the pathogenesis of gastric adenocarcinoma and …

The ideal nonviral vector delivers its nucleic acid cargo to a specific intracellular target.
Vectors enter cells mainly through endocytosis and are distributed to various intracellular …

Helicobacter pylori VacA is a channel-forming toxin unrelated to other known bacterial
toxins. Most H. pylori strains contain a vacA gene, but there is marked variation among …

Helicobacter pylori is a pathogenic bacterium that colonizes more than 50% of the world's
population, which leads to a tremendous medical burden. H. pylori infection is associated …