Genome control by SMC complexes
C Hoencamp, BD Rowland - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Many cellular processes require large-scale rearrangements of chromatin structure.
Structural maintenance of chromosomes (SMC) protein complexes are molecular machines …
Structural maintenance of chromosomes (SMC) protein complexes are molecular machines …
SMC complexes: from DNA to chromosomes
F Uhlmann - Nature reviews Molecular cell biology, 2016 - nature.com
SMC (structural maintenance of chromosomes) complexes—which include condensin,
cohesin and the SMC5–SMC6 complex—are major components of chromosomes in all …
cohesin and the SMC5–SMC6 complex—are major components of chromosomes in all …
A pathway for mitotic chromosome formation
INTRODUCTION During mitosis, cells compact their chromosomes into dense rod-shaped
structures to ensure their reliable transmission to daughter cells. Our work explores how …
structures to ensure their reliable transmission to daughter cells. Our work explores how …
A mitotic chromatin phase transition prevents perforation by microtubules
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete
bodies to enable microtubule-mediated transport of one genome copy to each of the newly …
bodies to enable microtubule-mediated transport of one genome copy to each of the newly …
Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle
The 1000 bull genomes project supports the goal of accelerating the rates of genetic gain in
domestic cattle while at the same time considering animal health and welfare by providing …
domestic cattle while at the same time considering animal health and welfare by providing …
Nuclear envelope assembly defects link mitotic errors to chromothripsis
Defects in the architecture or integrity of the nuclear envelope are associated with a variety
of human diseases. Micronuclei, one common nuclear aberration, are an origin for …
of human diseases. Micronuclei, one common nuclear aberration, are an origin for …
Self-organization of domain structures by DNA-loop-extruding enzymes
E Alipour, JF Marko - Nucleic acids research, 2012 - academic.oup.com
The long chromosomal DNAs of cells are organized into loop domains much larger in size
than individual DNA-binding enzymes, presenting the question of how formation of such …
than individual DNA-binding enzymes, presenting the question of how formation of such …
Condensins: universal organizers of chromosomes with diverse functions
T Hirano - Genes & development, 2012 - genesdev.cshlp.org
Condensins are multisubunit protein complexes that play a fundamental role in the structural
and functional organization of chromosomes in the three domains of life. Most eukaryotic …
and functional organization of chromosomes in the three domains of life. Most eukaryotic …
Dynamic chromatin organization without the 30-nm fiber
K Maeshima, S Ide, M Babokhov - Current opinion in cell biology, 2019 - Elsevier
Chromatin in eukaryotic cells is a negatively charged polymer composed of DNA, histones,
and various associated proteins. Over the past ten years, our view of chromatin has shifted …
and various associated proteins. Over the past ten years, our view of chromatin has shifted …
The structure and function of SMC and kleisin complexes
K Nasmyth, CH Haering - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract Protein complexes consisting of s tructural m aintenance of c hromosomes (SMC)
and kleisin subunits are crucial for the faithful segregation of chromosomes during cell …
and kleisin subunits are crucial for the faithful segregation of chromosomes during cell …