Cytokine imbalance as a biomarker of intervertebral disk degeneration
NA Shnayder, AV Ashhotov, VV Trefilova… - International Journal of …, 2023 - mdpi.com
The intervertebral disk degeneration (IDD) and its associated conditions are an important
problem in modern medicine. The onset of IDD may be in childhood and adolescence in …
problem in modern medicine. The onset of IDD may be in childhood and adolescence in …
The role of the complement system in disc degeneration and Modic changes
Disc degeneration and vertebral endplate bone marrow lesions called Modic changes are
prevalent spinal pathologies found in chronic low back pain patients. Their …
prevalent spinal pathologies found in chronic low back pain patients. Their …
Does vitamin K2 influence the interplay between diabetes mellitus and intervertebral disc degeneration in a rat model?
M Mahmoud, M Kokozidou, C Gögele, C Werner… - Nutrients, 2023 - mdpi.com
Intervertebral disc (IVD) degeneration is a common cause of low back pain in diabetes
mellitus type 2 (T2DM) patients. Its pathogenesis and the vitamin (vit.) K2 influence on this …
mellitus type 2 (T2DM) patients. Its pathogenesis and the vitamin (vit.) K2 influence on this …
Adipokine human Resistin promotes obesity-associated inflammatory intervertebral disc degeneration via pro-inflammatory cytokine cascade activation
Adipokine human Resistin (hResistin), is known to be associated with insulin resistance and
secrete low-grade pro-inflammatory cytokines in obesity. Although studies on low-grade …
secrete low-grade pro-inflammatory cytokines in obesity. Although studies on low-grade …
Diagnostic model based on key autophagy-related genes in intervertebral disc degeneration
Y Wang, Z Wang, Y Tang, Y Chen, C Fang, Z Li… - BMC Musculoskeletal …, 2023 - Springer
Background Current research on autophagy is mainly focused on intervertebral disc tissues
and cells, while there is few on human peripheral blood sample. therefore, this study …
and cells, while there is few on human peripheral blood sample. therefore, this study …
Terminal complement activation is induced by factors released from endplate tissue of disc degeneration patients and stimulates expression of catabolic enzymes in …
Terminal complement complex (TCC) deposition was identified in human degenerated
discs. To clarify the role of terminal complement activation in disc degeneration (DD), we …
discs. To clarify the role of terminal complement activation in disc degeneration (DD), we …
Reactive response of peripheral blood neutrophils of school-age adolescents with scoliosis
D Dychko, E Dychko, O Nekhanevych… - … en educación física …, 2024 - dialnet.unirioja.es
La escoliosis afecta negativamente a la salud física y mental de niños y adolescentes. La
deformidad escoliótica se desarrolla más rápidamente durante el período de crecimiento y …
deformidad escoliótica se desarrolla más rápidamente durante el período de crecimiento y …
Identification of key eRNAs for intervertebral disc degeneration by integrated multinomial bioinformatics analysis
Y Li, R Huang, J Ye, X Han, T Meng, D Song… - BMC Musculoskeletal …, 2024 - Springer
Background Intervertebral disc degeneration (IVDD) is a common degenerative condition
leading to abnormal stress distribution under load, causing intervertebral stenosis, facet joint …
leading to abnormal stress distribution under load, causing intervertebral stenosis, facet joint …
Interleukin-1β more than mechanical loading induces a degenerative phenotype in human annulus fibrosus cells, partially impaired by anti-proteolytic activity of …
RM Gonçalves, T Saggese, Z Yong… - … in Bioengineering and …, 2022 - frontiersin.org
Mesenchymal stem/stromal cell (MSC)–based therapies for low back pain and intervertebral
disc (IVD) degeneration have been emerging, despite the poor knowledge of their full …
disc (IVD) degeneration have been emerging, despite the poor knowledge of their full …
Oestrogen and Vibration Improve Intervertebral Disc Cell Viability and Decrease Catabolism in Bovine Organ Cultures
F Widmayer, C Neidlinger-Wilke, F Witz… - International Journal of …, 2023 - mdpi.com
Postmenopausal women are at an increased risk for intervertebral disc degeneration,
possibly due to the decrease in oestrogen levels. Low-magnitude, high-frequency vibration …
possibly due to the decrease in oestrogen levels. Low-magnitude, high-frequency vibration …