As important metabolic substrates, branched-chain amino acids (BCAAs) and fatty acids
(FAs) participate in many significant physiological processes, such as mitochondrial …

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …

Rationale: PGC1α (peroxisome proliferator-activated receptor gamma coactivator 1α)
represents an attractive target interfering bioenergetics and mitochondrial homeostasis, yet …

Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Peroxisome proliferator–activated receptor γ coactivator 1-α (PGC-1 α) is a highly conserved
transcriptional coactivator enriched in metabolically active tissues including liver, adipose …

Background The peroxisome proliferator-activated receptor-γ co-activator 1-α (PPARGC1A),
a key transcription factor involved in the control of metabolism and energy homeostasis, is …

Objectives This study is essentially a correlative study that examines the potential of reduced
levels of L-carnitine (LC) when combined with the pathophysiology of type 2 diabetes. The …

Background. Genome‐wide association study (GWAS) provides an unprecedented
opportunity to reveal substantial genetic contribution to type 2 diabetes mellitus (T2DM) and …

Aim To determine the association of peroxisome proliferator activated receptor gamma
coactivator 1 Gly482Ser variant with components of metabolic syndrome. Materials and …

Background and aim Adenosine triphosphate-binding cassette transporter A1 (ABCA1) and
hepatic lipase (LIPC) genes both play an important role in lipid metabolism. ABCA1 and …