The NF-κB signaling pathway is a key regulator of CRC cell proliferation, apoptosis,
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …

Nuclear factor-κB (NF-κB) has been widely implicated in the development and progression
of cancer. In colorectal cancer (CRC), NF-κB has a key role in cancer-related processes …

The malignancy of colorectal cancer (CRC) is connected with inflammation and tumor-
associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate …

Our review focuses on the colonic macrophage, a monocyte-derived, tissue-resident
macrophage, and the role it plays in health and disease, specifically in inflammatory …

Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …

Many cancers possess an incorrect number of chromosomes, a state described as
aneuploidy. Aneuploidy is often caused by Chromosomal Instability (CIN), a process of …

Simple Summary Colorectal cancer is one of the most common solid tumors in the
developed world. Although there have being many advances in treatment options in recent …

Most cancer‐related deaths result from the progressive growth of metastases. Patients with
peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is …

Many advanced cancers are characterized by metabolic disorders. A dietary therapeutic
strategy was proposed to inhibit tumor growth through administration of low-carbohydrate …

Tumor-associated macrophages (TAMs) that appear in every stage of cancer progression
are usually tumor-promoting cells and are present abundantly in the tumor-associated …