Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer
The NF-κB signaling pathway is a key regulator of CRC cell proliferation, apoptosis,
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …
NF-κB pathways in the development and progression of colorectal cancer
Nuclear factor-κB (NF-κB) has been widely implicated in the development and progression
of cancer. In colorectal cancer (CRC), NF-κB has a key role in cancer-related processes …
of cancer. In colorectal cancer (CRC), NF-κB has a key role in cancer-related processes …
[HTML][HTML] Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment
The malignancy of colorectal cancer (CRC) is connected with inflammation and tumor-
associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate …
associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate …
Colonic macrophage polarization in homeostasis, inflammation, and cancer
RA Isidro, CB Appleyard - American Journal of Physiology …, 2016 - journals.physiology.org
Our review focuses on the colonic macrophage, a monocyte-derived, tissue-resident
macrophage, and the role it plays in health and disease, specifically in inflammatory …
macrophage, and the role it plays in health and disease, specifically in inflammatory …
Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy
K Mortezaee, J Majidpoor - Cellular Oncology, 2022 - Springer
Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …
They provide a bridge between innate and adaptive immunity through releasing cytokines …
[HTML][HTML] The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity
AE Tijhuis, SC Johnson, SE McClelland - Molecular cytogenetics, 2019 - Springer
Many cancers possess an incorrect number of chromosomes, a state described as
aneuploidy. Aneuploidy is often caused by Chromosomal Instability (CIN), a process of …
aneuploidy. Aneuploidy is often caused by Chromosomal Instability (CIN), a process of …
[HTML][HTML] A 3D view of colorectal cancer models in predicting therapeutic responses and resistance
Simple Summary Colorectal cancer is one of the most common solid tumors in the
developed world. Although there have being many advances in treatment options in recent …
developed world. Although there have being many advances in treatment options in recent …
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis
S Peng, D Chen, J Cai, Z Yuan, B Huang… - Molecular …, 2021 - Wiley Online Library
Most cancer‐related deaths result from the progressive growth of metastases. Patients with
peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is …
peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is …
Ketogenic diet elicits antitumor properties through inducing oxidative stress, inhibiting MMP-9 expression, and rebalancing M1/M2 tumor-associated macrophage …
N Zhang, C Liu, L Jin, R Zhang, T Wang… - Journal of agricultural …, 2020 - ACS Publications
Many advanced cancers are characterized by metabolic disorders. A dietary therapeutic
strategy was proposed to inhibit tumor growth through administration of low-carbohydrate …
strategy was proposed to inhibit tumor growth through administration of low-carbohydrate …
Tumor-associated macrophages (TAMs): a critical activator in ovarian cancer metastasis
M Yin, J Shen, S Yu, J Fei, X Zhu, J Zhao… - OncoTargets and …, 2019 - Taylor & Francis
Tumor-associated macrophages (TAMs) that appear in every stage of cancer progression
are usually tumor-promoting cells and are present abundantly in the tumor-associated …
are usually tumor-promoting cells and are present abundantly in the tumor-associated …