Polymer materials provide solutions to some of the most pressing environmental,
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …

Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …

Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of
fibrosis progression. Understanding how cells sense and transmit mechanical cues in the …

The extracellular matrix mechanical properties regulate processes in development, cancer,
and fibrosis. Among the distinct mechanical properties, the vast majority of research has …

The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

Growing evidence suggests that the physical properties of the cellular microenvironment
influence cell migration. However, it is not currently understood how active physical …

A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

Phosphoinositides play a crucial role in regulating many cellular functions, such as actin
dynamics, signaling, intracellular trafficking, membrane dynamics, and cell–matrix adhesion …

Mechanical cues from the extracellular matrix (ECM) microenvironment are known to be
significant in modulating the fate of stem cells to guide developmental processes and …