[HTML][HTML] Epstein-Barr virus and systemic autoimmune diseases

G Houen, NH Trier - Frontiers in immunology, 2021 - frontiersin.org
Epstein-Barr Virus (EBV) is an extremely successful human herpes virus, which infects
essentially all human beings at some time during their life span. EBV infection and the …

Molecular basis of epstein–barr virus latency establishment and lytic reactivation

T Murata, A Sugimoto, T Inagaki, Y Yanagi… - Viruses, 2021 - mdpi.com
Epstein–Barr virus (EBV) is a causative agent of infectious mononucleosis and several types
of cancer. Like other herpesviruses, it establishes an asymptomatic, life-long latent infection …

Molecular mechanisms of viral oncogenesis in humans

NA Krump, J You - Nature Reviews Microbiology, 2018 - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …

EBV persistence—introducing the virus

DA Thorley-Lawson - Epstein Barr Virus Volume 1: One Herpes Virus …, 2015 - Springer
Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

CRISPR/Cas9-mediated genome editing of herpesviruses limits productive and latent infections

FR van Diemen, EM Kruse, MJG Hooykaas… - PLoS …, 2016 - journals.plos.org
Herpesviruses infect the majority of the human population and can cause significant
morbidity and mortality. Herpes simplex virus (HSV) type 1 causes cold sores and herpes …

Epstein-Barr virus and multiple sclerosis

G Houen, NH Trier, JL Frederiksen - Frontiers in immunology, 2020 - frontiersin.org
Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

How viral and intracellular bacterial pathogens reprogram the metabolism of host cells to allow their intracellular replication

W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2019 - frontiersin.org
Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

P Mrozek-Gorska, A Buschle, D Pich… - Proceedings of the …, 2019 - National Acad Sciences
Epstein–Barr virus (EBV) is a human tumor virus and a model of herpesviral latency. The
virus efficiently infects resting human B lymphocytes and induces their continuous …

Epstein–barr virus history and pathogenesis

H Yu, ES Robertson - Viruses, 2023 - mdpi.com
Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells

A Hassani, JR Corboy, S Al-Salam, G Khan - PloS one, 2018 - journals.plos.org
Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous
system (CNS). It is a major cause of neurological disability in young adults, particularly …