Complex regional pain syndrome

S Bruehl - Bmj, 2015 - bmj.com
Complex regional pain syndrome is a chronic pain condition characterized by autonomic
and inflammatory features. It occurs acutely in about 7% of patients who have limb fractures …

Clinical features and pathophysiology of complex regional pain syndrome

J Marinus, GL Moseley, F Birklein, R Baron… - The Lancet …, 2011 - thelancet.com
A complex regional pain syndrome (CRPS)—multiple system dysfunction, severe and often
chronic pain, and disability—can be triggered by a minor injury, a fact that has fascinated …

Whole‐body mapping of spatial acuity for pain and touch

F Mancini, A Bauleo, J Cole, F Lui, CA Porro… - Annals of …, 2014 - Wiley Online Library
Objective Tactile spatial acuity is routinely tested in neurology to assess the state of the
dorsal column system. In contrast, spatial acuity for pain is not assessed, having never been …

Mechanisms of disease: neuropathic pain—a clinical perspective

R Baron - Nature clinical practice Neurology, 2006 - nature.com
Neuropathic pain syndromes—pain after a lesion or disease of the peripheral or central
nervous system—are clinically characterized by spontaneous and evoked types of pain …

Chronic pain may change the structure of the brain

A May - PAIN®, 2008 - Elsevier
Recently, local morphologic alterations of the brain in areas ascribable to the transmission of
pain were detected in patients suffering from phantom pain, chronic back pain, irritable bowl …

An update on the pathophysiology of complex regional pain syndrome

S Bruehl, DS Warner - The Journal of the American Society of …, 2010 - pubs.asahq.org
Complex regional pain syndrome (CRPS) is a neuropathic pain disorder with significant
autonomic features. Few treatments have proven effective, in part, because of a historically …

Interventions for treating pain and disability in adults with complex regional pain syndrome‐an overview of systematic reviews

NE O'Connell, BM Wand, JH McAuley… - Cochrane Database …, 2013 - cochranelibrary.com
Background There is currently no strong consensus regarding the optimal management of
complex regional pain syndrome although a multitude of interventions have been described …

Peripheral input and its importance for central sensitization

R Baron, G Hans, AH Dickenson - Annals of neurology, 2013 - Wiley Online Library
Many pain states begin with damage to tissue and/or nerves in the periphery, leading to
enhanced transmitter release within the spinal cord and central sensitization. Manifestations …

Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1

MJ Sigtermans, JJ Van Hilten, MCR Bauer, MS Arbous… - Pain, 2009 - Elsevier
Complex Regional Pain Syndrome Type 1 (CRPS-1) responds poorly to standard pain
treatment. We evaluated if the N-methyl-d-aspartate receptor antagonist S (+)-ketamine …

Complex regional pain syndrome: a recent update

EL Goh, S Chidambaram, D Ma - Burns & trauma, 2017 - academic.oup.com
Complex regional pain syndrome (CRPS) is a debilitating condition affecting the limbs that
can be induced by surgery or trauma. This condition can complicate recovery and impair …