Objectives The objective of this study was to describe the mental health effects of high
ambient temperatures and heat waves, determine whether heat-related morbidity and …

Introduction Bipolar disorder (BD) is a severe mental disorder affecting 1–4% of the
population worldwide. It is characterized by periods of (hypo) manic and depressive …

Background The relationship between sunlight hours, temperature, and suicide has been
investigated in many previous studies, but with inconsistent findings. We conducted this …

As climate change exerts wide ranging health impacts, there is a surge of interest in the
associations between climatic factors and mental and behavioral disorders (MBDs). Existing …

Converging translational evidence has implicated elevated immune-inflammatory signaling
activity in the pathoetiology of mood disorders, including major depressive disorder and …

Abstract Background Mental disorders (MDs) are behavioral or mental patterns that cause
significant distress or impairment of personal functioning. Previously, temperature has been …

Developing novel therapeutics for bipolar disorder (BD) has been hampered by limited
mechanistic knowledge how sufferers switch between mania and depression—how the …

Bipolar disorder (BD) is a unique disorder that transcends domains of function since the
same patient can exhibit depression or mania, states with polar opposite mood symptoms …

BACKGROUND: Mania/hypomania is the hallmark feature of bipolar disorder. This paper
aims to review the current evidence in relation to factors hypothesised to precipitate bipolar …

Bipolar disorder (BD) has a multifactorial etiology with heterogeneous clinical presentations.
Around 25% of BD patients may present with a depressive seasonal pattern (SP). However …