[HTML][HTML] Pathophysiological bases of comorbidity in migraine

C Altamura, I Corbelli, M De Tommaso… - Frontiers in human …, 2021 - frontiersin.org
Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …

Shedding light on photophobia

KB Digre, KC Brennan - Journal of Neuro-ophthalmology, 2012 - journals.lww.com
Photophobia is a common yet debilitating symptom seen in many ophthalmic and neurologic
disorders. Despite its prevalence, it is poorly understood and difficult to treat. However, the …

[HTML][HTML] Neural control of choroidal blood flow

A Reiner, MEC Fitzgerald, N Del Mar, C Li - Progress in retinal and eye …, 2018 - Elsevier
The choroid is richly innervated by parasympathetic, sympathetic and trigeminal sensory
nerve fibers that regulate choroidal blood flow in birds and mammals, and presumably other …

Autologous serum tears for treatment of photoallodynia in patients with corneal neuropathy: efficacy and evaluation with in vivo confocal microscopy

S Aggarwal, A Kheirkhah, BM Cavalcanti, A Cruzat… - The ocular …, 2015 - Elsevier
Objective Patients suffering from corneal neuropathy may present with photoallodynia; ie,
increased light sensitivity, frequently with a normal slit-lamp examination. This study aimed …

[HTML][HTML] Mechanisms and pathways of pain photobiomodulation: a narrative review

K Cheng, LF Martin, MJ Slepian, AM Patwardhan… - The journal of pain, 2021 - Elsevier
A growing body of evidence supports the modulation of pain by light exposure. As such,
phototherapy is being increasingly utilized for the management of a variety of pain …

Diagnosis, pathophysiology, and treatment of photophobia

BJ Katz, KB Digre - Survey of ophthalmology, 2016 - Elsevier
Photophobia, an abnormal intolerance to light, is associated with a number of ophthalmic
and neurologic conditions. In the presence of normal neurologic and ophthalmologic …

Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

A Recober, A Kuburas, Z Zhang… - Journal of …, 2009 - Soc Neuroscience
Migraine is a chronic neurological disorder characterized by recurrent episodes of severe
unilateral throbbing head pain and associated symptoms, such as photophobia. Our current …

Bright light activates a trigeminal nociceptive pathway

K Okamoto, A Tashiro, Z Chang, DA Bereiter - PAIN®, 2010 - Elsevier
Bright light can cause ocular discomfort and/or pain; however, the mechanism linking
luminance to trigeminal nerve activity is not known. In this study we identify a novel reflex …

Photophobia: shared pathophysiology underlying dry eye disease, migraine and traumatic brain injury leading to central neuroplasticity of the trigeminothalamic …

RJ Diel, D Mehra, R Kardon, DC Buse… - British Journal of …, 2021 - bjo.bmj.com
Background Photophobia is a potentially debilitating symptom often found in dry eye
disease (DE), migraine and traumatic brain injury (TBI). Methods We conducted a review of …

Photophobia in headache disorders: characteristics and potential mechanisms

Y Wang, S Wang, T Qiu, Z Xiao - Journal of Neurology, 2022 - Springer
Photophobia is present in multiple types of headache disorders. The coexistence of
photophobia and headache suggested the potential reciprocal interactions between visual …