Frequency and mortality of sepsis and septic shock in China: a systematic review and meta-analysis

YC Liu, Y Yao, MM Yu, YL Gao, AL Qi, TY Jiang… - BMC infectious …, 2022 - Springer
Background Sepsis, a life-threatening organ dysfunction induced by infection, is a major
public health problem. This study aimed to evaluate the frequency and mortality of sepsis …

Immune dysregulation in sepsis: experiences, lessons and perspectives

M Cao, G Wang, J Xie - Cell Death Discovery, 2023 - nature.com
Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host
responses to infection. Not only does sepsis pose a serious hazard to human health, but it …

Clinical characteristics of patients who died of coronavirus disease 2019 in China

J Xie, Z Tong, X Guan, B Du, H Qiu - JAMA network open, 2020 - jamanetwork.com
The outbreak of coronavirus disease 2019 (COVID-19) has been very severe in China. 1 As
of March 2020, many tens of thousands of patients have had confirmed COVID-19, and …

National incidence and mortality of hospitalized sepsis in China

L Weng, Y Xu, P Yin, Y Wang, Y Chen, W Liu, S Li… - Critical Care, 2023 - Springer
Background Sepsis is a leading cause of preventable death around the world. Population-
based estimation of sepsis incidence is lacking in China. In this study, we aimed to estimate …

Interpretable machine learning for early prediction of prognosis in sepsis: a discovery and validation study

C Hu, L Li, W Huang, T Wu, Q Xu, J Liu… - Infectious diseases and …, 2022 - Springer
Introduction This study aimed to develop and validate an interpretable machine-learning
model based on clinical features for early predicting in-hospital mortality in critically ill …

Effect of an herbal-based injection on 28-day mortality in patients with sepsis: the EXIT-SEP randomized clinical trial

S Liu, C Yao, J Xie, H Liu, H Wang, Z Lin… - JAMA internal …, 2023 - jamanetwork.com
Importance Previous research has suggested that Xuebijing injection (XBJ), an herbal-
based intravenous preparation, may reduce mortality among patients with sepsis. Objective …

Circulating histones in sepsis: potential outcome predictors and therapeutic targets

Y Li, D Wan, X Luo, T Song, Y Wang, Q Yu… - Frontiers in …, 2021 - frontiersin.org
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection and is associated with high morbidity and mortality. Circulating …

The role of macrophages polarization in sepsis-induced acute lung injury

Z Wang, Z Wang - Frontiers in immunology, 2023 - frontiersin.org
Sepsis presents as a severe infectious disease frequently documented in clinical settings.
Characterized by its systemic inflammatory response syndrome, sepsis has the potential to …

[PDF][PDF] 中国脓毒症早期预防与阻断急诊专家共识

共识, 解读 - 临床急诊杂志, 2020 - medi-guide.meditool.cn
中国脓毒症早期预防与阻断急诊专家共识 Page 1 2020年 临床急诊杂志 21卷7期
JournalofClinicalEmergency(China) ·共识·解读· [编者按]脓毒症是目前医学界面临的重大难题与 …

Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases

A Ou, J Zhang, Y Fang, R Wang, X Tang… - Acta Pharmacologica …, 2021 - nature.com
Sepsis is a dysregulated immune response to infection and potentially leads to life-
threatening organ dysfunction, which is often seen in serious Covid-19 patients. Disulfiram …