Altered cellular metabolism is a hallmark of gliomas. Propelled by a set of recent
technological advances, new insights into the molecular mechanisms underlying glioma …

We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …

Simple Summary Radiogenomics is a relatively new advancement in the understanding of
the biology and behaviour of cancer in response to conventional treatments. One of the most …

Glioblastoma ranks among the most aggressive and lethal of all human cancers.
Functionally defined glioma stem cells (GSC) contribute to this poor prognosis by driving …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

Major depressive disorder is one of the most common mental illnesses as it affects more
than 350 million people globally. Major depressive disorder is etiologically complex and …

Investigation into intratumoral heterogeneity (ITH) of the epigenome is in a formative stage.
The patterns of tumor evolution inferred from epigenetic ITH and genetic ITH are remarkably …

MALDI mass spectrometry imaging is able to simultaneously determine the spatial
distribution of hundreds of molecules directly from tissue sections, without labeling and …

Despite our growing molecular-level understanding of glioblastoma (GBM), treatment
modalities remain limited. Recent developments in the mechanisms of cell fate regulation …

The highly lethal brain cancer glioblastoma (GBM) poses a daunting challenge because the
blood-brain barrier renders potentially druggable amplified or mutated oncoproteins …