Peptide receptor radionuclide therapy (PRRT): innovations and improvements

E Merola, CM Grana - Cancers, 2023 - mdpi.com
Simple Summary This article discusses the use of peptide receptor radionuclide therapy
(PRRT) as a key treatment method for advanced, unresectable neuroendocrine tumors. It …

Surgery, liver directed therapy and peptide receptor radionuclide therapy for pancreatic neuroendocrine tumor liver metastases

R Ngongoni, B Visser - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors are tumors with varying degrees of
aggressiveness. The most frequent site of metastasis is the liver. Treatment methods for …

177Lu-DOTATATE Plus Radiosensitizing Capecitabine Versus Octreotide Long-Acting Release as First-Line Systemic Therapy in Advanced Grade 1 or 2 …

S Satapathy, BR Mittal, A Sood, A Sood… - JCO Global …, 2021 - ascopubs.org
PURPOSE To compare the efficacy and safety of 177Lu-DOTATATE plus radiosensitizing
capecitabine and octreotide long-acting release (LAR) as first-line systemic therapy in …

Predictive factors for resistant disease with Medical/Radiologic/Liver-directed anti-tumor treatments in patients with advanced pancreatic neuroendocrine neoplasms …

L Lee, I Ramos-Alvarez, RT Jensen - Cancers, 2022 - mdpi.com
Simple Summary Tumor resistance, both primary and acquired, is leading to increased
complexity in the nonsurgical treatment of patients with advanced panNENs, which would be …

Theranostic options for radioiodine-refractory differentiated thyroid carcinoma: recent advances, challenges, and road ahead

S Satapathy, C Bal - Frontiers in Endocrinology, 2022 - frontiersin.org
Radioiodine-refractory differentiated thyroid cancer (RAIR-DTC), though uncommon,
presents a considerable therapeutic challenge with poor long-term outcomes. Currently …

Peptide receptor chemoradionuclide therapy for neuroendocrine neoplasms: a systematic review

DS Chan, AL Kanagaratnam… - Journal of …, 2023 - Wiley Online Library
Peptide receptor chemoradionuclide therapy (PRCRT), the addition of radiosensitising
chemotherapy to peptide receptor radionuclide therapy (PRRT), has been used in individual …

Gastro-enteric-pancreatic neuroendocrine tumor treatment: 177Lu-DOTATATE

Y Sanli, D Denizmen, RM Subramaniam - PET clinics, 2023 - pet.theclinics.com
Diagnosis of neuroendocrine tumors (NETs) has increased significantly over the past
decade. Successful detection of metastatic diseases has been achieved through …

Strategies towards improving clinical outcomes of peptide receptor radionuclide therapy

NS Minczeles, J Hofland, WW de Herder… - Current Oncology …, 2021 - Springer
Abstract Purpose of Review Peptide receptor radionuclide therapy (PRRT) with [177 Lu-
DOTA 0, Tyr 3] octreotate is an effective and safe second-or third-line treatment option for …

Hematological Markers as Predictors of Treatment Outcomes with Lutetium 177 (177Lu)-DOTATATE in Patients with Advanced Neuroendocrine Tumors

S Satapathy, A Bhattacharya, A Sood… - Cancer Biotherapy & …, 2022 - liebertpub.com
Background: Chronic inflammation has been linked to the development and prognosis of
neuroendocrine tumors (NETs). The current study intended to evaluate the role of peripheral …

Alpha before beta: exceptional response to first-line 225Ac-DOTATATE in a patient of metastatic neuroendocrine tumor with extensive skeletal involvement

S Satapathy, A Sood, CK Das, AJ Kavanal… - Clinical Nuclear …, 2022 - journals.lww.com
The utility of β-emitter 177 Lu-DOTATATE in patients of neuroendocrine tumors (NETs) with
widespread skeletal metastases is limited by its relatively modest response rates and a …