Analysis of the literature involving computational modeling of diseases and drug design with
the aid of experimental spectroscopic techniques reveals that this specific combination of …

In 1980 sulfamic acid and its N-substituted derivatives were reviewed in Chemical Reviews,
1 effectively updating an earlier 1940 review 2 also in Chemical Reviews. In 1991 the …

Key factors contributing to early stages of atherosclerosis and plaque development include
the pro-inflammatory cytokines Interferon (IFN) α, IFNγ and Interleukin (IL)-6 and Toll-like …

A stereoselective and self-promoted glycosylation for the synthesis of various N-glycosides
and glycosyl sulfonamides from trichloroacetimidates is presented. No additional catalysts or …

Background: There are no reliable markers of malignancy in phaeochromocytomas (PCC)
and paragangliomas (PGL). We investigated the relevance of the mammalian target of …

N‐Glycosyl N‐sulfonyl amides have been synthesized by a self‐promoted glycosylation, ie
without any catalysts, promotors or additives. When the reactions were carried out at lower …

The transmembrane isoforms of carbonic anhydrase (hCA IX and XII) have been shown to
be linked to carcinogenesis and their inhibition to arrest primary tumor and metastases …

Native glycosidic bonds in carbohydrates, are sensitive to the presence of enzymes. Thus,
design of small molecule mimics (glycomimetics) is an active area of research. This review …

The conformational behavior of 2, 3, 4, 6-tetra-O-acetyl-β-d-mannopyranosyl
methanesulfonamide has been investigated from a combined theoretical and experimental …

El acoplamiento de carbohidratos a los farmacóforos adecuados, ha probado ser altamente
útil en el desarrollo de sustancias que puedan ser empleados como inhibidores …