Decoding the tumour-modulatory roles of LIMK2
Abstract LIM domains kinase 2 (LIMK2) is a 72 kDa protein that regulates actin and
cytoskeleton reorganization. Once phosphorylated by its upstream activator (ROCK1) …
cytoskeleton reorganization. Once phosphorylated by its upstream activator (ROCK1) …
[HTML][HTML] Deacetylation of Histones and Non-histone Proteins in Inflammatory Diseases and Cancer Therapeutic Potential of Histone Deacetylase Inhibitors
E Man, S Evran - Current Genomics, 2023 - ncbi.nlm.nih.gov
Epigenetic changes play an important role in the pathophysiology of autoimmune diseases
such as allergic asthma, multiple sclerosis, lung diseases, diabetes, cystic fibrosis …
such as allergic asthma, multiple sclerosis, lung diseases, diabetes, cystic fibrosis …
Class I HDAC Inhibition Leads to a Downregulation of FANCD2 and RAD51, and the Eradication of Glioblastoma Cells
M Drzewiecka, D Jaśniak… - Journal of Personalized …, 2023 - mdpi.com
HDAC inhibitors (HDACi) hold great potential as anticancer therapies due to their ability to
regulate the acetylation of both histone and non-histone proteins, which is frequently …
regulate the acetylation of both histone and non-histone proteins, which is frequently …