Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

Advances in biomedical research have generated an unprecedented number of potential
targets for therapeutic intervention to treat disease or delay disease progression …

Multipotent mesenchymal stromal cells (MSCs) have potential therapeutic benefit for the
treatment of neurological diseases and injury. MSCs interact with and alter brain …

The advent of mesenchymal stem cell (MSC)-based therapies for clinical therapeutics has
been an exciting and new innovation for the treatment of a variety of diseases associated …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Mesenchymal stem or stromal cells (MSCs) are pluripotent cells implicated in a broad range
of physiological events, including organogenesis and maintenance of tissue homeostasis as …

AIMS: To identify better cells for the treatment of diabetic critical limb ischemia (CLI) and foot
ulcer in a pilot trial. METHODS: Under ordinary treatment, the limbs of 41 type 2 diabetic …

Elucidating the molecular mechanisms that regulate human stromal (mesenchymal) stem
cell (hMSC) differentiation into osteogenic lineage is important for the development of …

Human stromal (mesenchymal) stem cells (hMSCs) are multipotent stem cells with ability to
differentiate into mesoderm-type cells eg osteoblasts and adipocytes and thus they are …