Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

M Al-Azab, M Safi, E Idiiatullina, F Al-Shaebi… - Cellular & Molecular …, 2022 - Springer
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

The potential of fasting-mimicking diet as a preventive and curative strategy for Alzheimer's disease

V Boccardi, M Pigliautile, AG Guazzarini, P Mecocci - Biomolecules, 2023 - mdpi.com
This review examines the potential of fasting-mimicking diets (FMDs) in preventing and
treating Alzheimer's disease (AD). FMDs are low-calorie diets that mimic the physiological …

The mechanism of stem cell aging

L Mi, J Hu, N Li, J Gao, R Huo, X Peng, N Zhang… - Stem cell reviews and …, 2022 - Springer
Stem cells have self-renewal ability and multi-directional differentiation potential. They have
tissue repair capabilities and are essential for maintaining the tissue homeostasis. The …

Targeting the stem cell niche micro-environment as therapeutic strategies in aging

R Farahzadi, B Valipour, S Montazersaheb… - Frontiers in Cell and …, 2023 - frontiersin.org
Adult stem cells (ASCs) reside throughout the body and support various tissue. Owing to
their self-renewal capacity and differentiation potential, ASCs have the potential to be used …

Resveratrol mediated regulation of hippocampal neuroregenerative plasticity via SIRT1 pathway in synergy with Wnt signaling: Neurotherapeutic implications to …

K Surya, N Manickam… - Journal of …, 2023 - content.iospress.com
Alzheimer's disease (AD) is a major form of dementia. Abnormal amyloidogenic event-
mediated degeneration of cholinergic neurons in the cognitive centers of the brain has been …

Role of diet in stem and cancer stem cells

F Puca, M Fedele, D Rasio, S Battista - International journal of molecular …, 2022 - mdpi.com
Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer.
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …

Neurotrophic effects of intermittent fasting, calorie restriction and exercise: a review and annotated bibliography

E Mayor - Frontiers in Aging, 2023 - frontiersin.org
In the last decades, important progress has been achieved in the understanding of the
neurotrophic effects of intermittent fasting (IF), calorie restriction (CR) and exercise …

The molecular mechanism of polyphenols in the regulation of ageing hallmarks

QC Pereira, TW Dos Santos, IM Fortunato… - International Journal of …, 2023 - mdpi.com
Ageing is a complex process characterized mainly by a decline in the function of cells,
tissues, and organs, resulting in an increased risk of mortality. This process involves several …

How calorie restriction slows aging: an epigenetic perspective

GM Lim, N Maharajan, GW Cho - Journal of Molecular Medicine, 2024 - Springer
Genomic instability and epigenetic alterations are some of the prominent factors affecting
aging. Age-related heterochromatin loss and decreased whole-genome DNA methylation …

Camphorquinone promotes the antisenescence effect via activating AMPK/SIRT1 in stem cells and D-galactose-induced aging mice

N Maharajan, GW Cho - Antioxidants, 2021 - mdpi.com
Terpenoids are a wide class of secondary metabolites with geroprotective properties that
can alter the mechanism of aging and aging-related diseases. Camphorquinone (CQ) is a …