Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system

L Zhou, JY Xiong, YQ Chai, L Huang, ZY Tang… - Frontiers in …, 2022 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

Roles of the unsaturated fatty acid docosahexaenoic acid in the central nervous system: Molecular and cellular insights

AB Petermann, M Reyna-Jeldes, L Ortega… - International journal of …, 2022 - mdpi.com
Fatty acids (FAs) are essential components of the central nervous system (CNS), where they
exert multiple roles in health and disease. Among the FAs, docosahexaenoic acid (DHA) …

The interrelationship of metabolic syndrome and neurodegenerative diseases with focus on brain-derived neurotrophic factor (BDNF): Kill two birds with one stone

S Motamedi, I Karimi, F Jafari - Metabolic brain disease, 2017 - Springer
The brain-derived neurotrophic factor (BDNF) is involved in metabolic syndrome (MetS) and
neurodegenerative diseases (NDD) like Alzheimer's disease, Huntington's disease …

Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity …

SM Ahmadi-Soleimani, GY Amiry, E Khordad… - Life Sciences, 2023 - Elsevier
In the present study, the main objective was to reveal whether treatment by Omega-3 fatty
acids could prevent the adverse effects of adolescent nicotine withdrawal on spatial and …

[HTML][HTML] How fish consumption prevents the development of Major Depressive Disorder? A comprehensive review of the interplay between n-3 PUFAs, LTP and BDNF

Ł Kołodziej, PL Czarny, S Ziółkowska, K Białek… - Progress in Lipid …, 2023 - Elsevier
MDD (major depressive disorder) is a highly prevalent mental disorder with a complex
etiology involving behavioral and neurochemical factors as well as environmental stress …

Omega-3 fatty acids prevent nicotine withdrawal-induced exacerbation of anxiety and depression by affecting oxidative stress balance, inflammatory response, BDNF …

GY Amiry, M Haidary, H Azhdari-Zarmehri… - European Journal of …, 2023 - Elsevier
Adolescents are known to be more vulnerable than adults to the adverse effects of nicotine
dependence. In the present study, we aimed to investigate whether adolescent nicotine …

Exenatide reverts the high-fat-diet-induced impairment of BDNF signaling and inflammatory response in an animal model of Alzheimer's disease

M Bomba, A Granzotto, V Castelli… - Journal of …, 2019 - content.iospress.com
Alzheimer's disease (AD) is a multifactorial condition in which, along with amyloid-(A) and
tau-related pathology, the synergistic activity of co-morbidity factors promote the onset and …

Electroacupuncture for weight loss by regulating microglial polarization in the arcuate nucleus of the hypothalamus

Y He, K Yang, L Zhang, M Zhan, XW Xia, HF Wang… - Life Sciences, 2023 - Elsevier
Electroacupuncture (EA) has a weight loss effect, but the underlying molecular mechanisms
of weight loss with EA have not been fully elucidated. This study aimed to investigate the …

Omega-3 fatty acids attenuate brain alterations in high-fat diet-induced obesity model

AH de Mello, RB Schraiber, MPS Goldim… - Molecular …, 2019 - Springer
This study evaluated the effects of omega-3 on inflammation, oxidative stress, and energy
metabolism parameters in the brain of mice subjected to high-fat diet-induced obesity model …

n-3 fatty acid and its metabolite 18-HEPE ameliorate retinal neuronal cell dysfunction by enhancing Müller BDNF in diabetic retinopathy

A Suzumura, H Kaneko, Y Funahashi, K Takayama… - Diabetes, 2020 - Am Diabetes Assoc
Diabetic retinopathy (DR) is a widespread vision-threatening disease, and neuroretinal
abnormality should be considered as an important problem. Brain-derived neurotrophic …