Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine

R Singhal, YM Shah - Journal of Biological Chemistry, 2020 - ASBMB
The gastrointestinal tract is a highly proliferative and regenerative tissue. The intestine also
harbors a large and diverse microbial population collectively called the gut microbiome …

The structure-based reaction mechanism of urease, a nickel dependent enzyme: tale of a long debate

L Mazzei, F Musiani, S Ciurli - JBIC Journal of Biological Inorganic …, 2020 - Springer
This review is an attempt to retrace the chronicle that starts from the discovery of the role of
nickel as the essential metal ion in urease for the enzymatic catalysis of urea, a key step in …

Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome

Q Liu, Q Su, F Zhang, HM Tun, JWY Mak… - Nature …, 2022 - nature.com
Our knowledge of the role of the gut microbiome in acute coronavirus disease 2019 (COVID-
19) and post-acute COVID-19 is rapidly increasing, whereas little is known regarding the …

[HTML][HTML] Ureases: Historical aspects, catalytic, and non-catalytic properties–A review

K Kappaun, AR Piovesan, CR Carlini… - Journal of advanced …, 2018 - Elsevier
Abstract Urease (urea amidohydrolase, EC 3.5. 1.5) is a nickel-containing enzyme produced
by plants, fungi, and bacteria that catalyzes the hydrolysis of urea into ammonia and …

[HTML][HTML] Recent advances in design of new urease inhibitors: A review

P Kafarski, M Talma - Journal of advanced research, 2018 - Elsevier
Urease is a nickel-dependent metalloenzyme found in plants, some bacteria, and fungi.
Bacterial enzyme is of special importance since it has been demonstrated as a potent …

Nickel impact on human health: An intrinsic disorder perspective

B Zambelli, VN Uversky, S Ciurli - … et Biophysica Acta (BBA)-Proteins and …, 2016 - Elsevier
The interplay of the presence of nickel and protein disorder in processes affecting human
health is the focus of the present review. Many systems involving nickel as either a cofactor …

A DNAzyme‐Based Colorimetric Paper Sensor for Helicobacter pylori

MM Ali, M Wolfe, K Tram, J Gu, CDM Filipe… - Angewandte …, 2019 - Wiley Online Library
The reliable detection of pathogenic bacteria in complex biological samples using simple
assays or devices remains a major challenge. Herein, we report a simple colorimetric paper …

Mechanisms of fungal dissemination

AB Strickland, M Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …

Nanotechnology for targeted detection and removal of bacteria: opportunities and challenges

MJ Hajipour, AA Saei, ED Walker, B Conley… - Advanced …, 2021 - Wiley Online Library
The emergence of nanotechnology has created unprecedented hopes for addressing
several unmet industrial and clinical issues, including the growing threat so‐termed …

[HTML][HTML] Selective substrate uptake: The role of ATP-binding cassette (ABC) importers in pathogenesis

KJ Tanaka, S Song, K Mason, HW Pinkett - Biochimica et Biophysica Acta …, 2018 - Elsevier
The uptake of nutrients, including metals, amino acids and peptides are required for many
biological processes. Pathogenic bacteria scavenge these essential nutrients from …