Introduction Defects in the maturation stage of amelogenesis result in a normal volume of
enamel but insufficient mineralization, called hypomineralization. Molar‐incisor …

The major mineralized tissues are bone and teeth, which share several mechanisms
governing their development and mineralization. This crossover includes the hormones that …

Understanding cell types and mechanisms of dental growth is essential for reconstruction
and engineering of teeth. Therefore, we investigated cellular composition of growing and …

Tooth enamel secreted by ameloblasts (AMs) is the hardest material in the human body,
acting as a shield to protect the teeth. However, the enamel is gradually damaged or …

Tooth enamel is the outer covering of tooth crowns, the hardest material in the mammalian
body, yet fracture resistant. The extremely high content of 95 wt% calcium phosphate in …

Ameloblasts are specialized cells derived from the dental epithelium that produce enamel, a
hierarchically structured tissue comprised of highly elongated hydroxylapatite (OHAp) …

Dental caries, a chronic and irreversible disease caused by caries-causing bacteria, has
been listed as one of the three major human diseases to be prevented and treated …

With increasing life expectancy, demands for dental tissue and whole-tooth regeneration are
becoming more significant. Despite great progress in medicine, including regenerative …

In modern dentistry, a minimally invasive management of early caries lesions or early-stage
erosive tooth wear (ETW) with synthetic remineralization systems has become …

Dental enamel is a specialized tissue that has adapted over millions of years of evolution to
enhance the survival of a variety of species. In humans, enamel evolved to form the exterior …