Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products

P Pandi, R Bulusu, N Kommineni, W Khan… - International journal of …, 2020 - Elsevier
Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …

Continuous manufacturing and molecular modeling of pharmaceutical amorphous solid dispersions

AG Nambiar, M Singh, AR Mali, DR Serrano… - AAPS …, 2022 - Springer
Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

Sunflower oil as renewable biomass source to develop highly effective oil-soluble catalysts for in-situ combustion of heavy oil

A Tajik, A Farhadian, MA Khelkhal… - Chemical Engineering …, 2023 - Elsevier
In-situ combustion has received much attention in the last few decades for enhanced heavy
oil recovery processes. Although a wide part of research efforts has only focused on the …

Effect of Ligand Structure on the Kinetics of Heavy Oil Oxidation: Toward Biobased Oil-Soluble Catalytic Systems for Enhanced Oil Recovery

A Farhadian, MA Khelkhal, A Tajik… - Industrial & …, 2021 - ACS Publications
In recent years, protection of the environment from activities associated with enhanced oil
recovery has been considered a crucial priority for decision-makers in the international …

Crystallization kinetics and glass-forming ability of rapidly crystallizing drugs studied by Fast Scanning Calorimetry

SE Lapuk, TA Mukhametzyanov, C Schick… - International Journal of …, 2021 - Elsevier
The use of the amorphous forms of drugs is a modern approach for the enhancement of
bioavailability. At the same time, the high cooling rate needed to obtain the metastable …

Differential scanning calorimetry investigation of crystallization kinetics and glass-forming ability of sulfonamides

SE Lapuk, MA Ziganshin, RA Larionov… - Journal of Non …, 2023 - Elsevier
Robust determination of the parameters governing the stability of the amorphous drugs is
one of the key tasks of modern pharmaceutics. The kinetic stability of such systems is of …

Non-Isothermal Crystallization Kinetics of PBSu/Biochar Composites Studied by Isoconversional and Model Fitting Methods

K Papadopoulou, E Tarani, K Chrissafis, O Mašek… - Polymers, 2023 - mdpi.com
Non-isothermal crystallization of Poly (butylene succinate)(PBSu)/biochar composites was
studied at various constant cooling rates using differential scanning calorimetry. The …

Glass transition kinetics and physical aging of polyvinylpyrrolidones with different molecular masses

SE Lapuk, MA Ponomareva, AV Galukhin… - …, 2022 - ACS Publications
The stability of glassy materials, including polymer-based ones, is one of the important
subjects of material science and technology. This interest is due to the dependence of the …

Nucleation and crystallization of deeply supercooled benzocaine, a rapidly crystallizing organic compound: A Fast scanning calorimetry investigation

TA Mukhametzyanov, RA Andrianov… - Thermochimica …, 2023 - Elsevier
Investigation of nucleation and crystal growth in rapidly crystallizing systems represents a
serious experimental challenge. Fast Scanning Calorimetry (FSC) was successfully used to …

Kinetic stability and glass-forming ability of thermally labile quinolone antibiotics

SE Lapuk, TA Mukhametzyanov, C Schick… - Molecular …, 2023 - ACS Publications
The application of drugs in the amorphous state is one way to improve their bioavailability.
As such, the determination of the optimal conditions for production and the assessment of …