Rutaecarpine: a promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu)

K Tian, J Li, S Xu - Pharmacological Research, 2019 - Elsevier
Rutaecarpine is a bioactive alkaloid isolated from Evodia rutaecarpa (Wu Zhu Yu, Family:
Rutaceae), a versatile medicinal herb which is clinically used to treat headache, abdominal …

Traditional uses, phytochemistry, pharmacology, pharmacokinetics and toxicology of the fruit of Tetradium ruticarpum: A review

M Li, C Wang - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance The fruit of Tetradium ruticarpum (FTR) known as Tetradii
fructus or Evodiae fructus (Wu-Zhu-Yu in Chinese) is a versatile herbal medicine which has …

[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

The pharmacokinetics profiles, pharmacological properties, and toxicological risks of dehydroevodiamine: A review

S Fu, L Liao, Y Yang, Y Bai, Y Zeng, H Wang… - Frontiers in …, 2022 - frontiersin.org
Dehydroevodiamine (DHE) is a quinazoline alkaloid isolated from Evodiae Fructus (EF,
Wuzhuyu in Chinese, Rutaceae family), a well-known traditional Chinese medicine (TCM) …

Natural products as the calcium channel blockers for the treatment of arrhythmia: Advance and prospect

L Xiao, XJ Chen, JK Feng, WN Li, S Yuan, Y Hu - Fitoterapia, 2023 - Elsevier
Arrhythmia is one of the commonly heart diseases with observed abnormal heart-beat
rhythm that caused by the obstacles of cardiac activity and conduction. The arrhythmic …

Traditional Chinese medicine Euodiae Fructus: botany, traditional use, phytochemistry, pharmacology, toxicity and quality control

SJ Xiao, XK Xu, W Chen, JY Xin, WL Yuan… - Natural Products and …, 2023 - Springer
Euodiae Fructus, referred to as “Wuzhuyu” in Chinese, has been used as local and
traditional herbal medicines in many regions, especially in China, Japan and Korea, for the …

The canine chronic atrioventricular block model in cardiovascular preclinical drug research

V Loen, MA Vos… - British Journal of …, 2022 - Wiley Online Library
Ventricular cardiac arrhythmia is a life threating condition arising from abnormal functioning
of many factors in concert. Animal models mirroring human electrophysiology are essential …

Dehydroevodiamine ameliorates indomethacin-induced gastric injury via inhibition of ERK and p38 signaling pathway

Y Wei, S Ren, J Wang, Y Wang, Y Cui, M Tian, R Wang… - Phytomedicine, 2021 - Elsevier
Background Dehydroevodiamine (DHE), a pivotal quinazoline alkaloid isolated from Fructus
Evodiae (Tetradium ruticarpum (A. Juss.) Hartley), has various pharmacological effects …

[HTML][HTML] A review on plants and herbal components with antiarrhythmic activities and their interaction with current cardiac drugs

A Beik, S Joukar, H Najafipour - Journal of Traditional and Complementary …, 2020 - Elsevier
This paper aimed to compile information on plants or their compounds which have
experimentally shown antiarrhythmic effect and to scrutinize the efficacy and potency of them …

Mechanism and Pharmacodynamic Substance Basis of Raw and Wine‐Processed Evodia rutaecarpa on Smooth Muscle Cells of Dysmenorrhea Mice

Y Liu, H Li, L Chen, H Zhao, J Liu… - Pain Research and …, 2023 - Wiley Online Library
Objectives. Evodia rutaecarpa (ER) is a well‐known herbal Chinese medicine traditionally
used for analgesia in dysmenorrhea, headaches, abdominal pain, etc. Notably, the …