Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

The need for bone tissue regeneration is continuously expanding due to the improvement of
life quality and the consequent increase in life expectancy. Although natural bone grafts …

Autologous bone grafting is currently considered as the gold standard to restore bone
defects. However, clinical benefit is not guaranteed and there is an associated 8–39 …

Background The hierarchical porous structure and surface topography of calcium phosphate
(CaP) bioceramics have a crucial impact on their osteoinductivity. Purpose To fabricate a …

Microstructure is essential for inductive bone formation in calcium phosphate materials after
soft tissue implantation. We hereby evaluated activities (cell attachment, proliferation …

Improvement of synthetic bone graft substitutes as suitable alternatives to a patient's own
bone graft remains a challenge in biomaterials research. Our goal was to answer the …

Bone has a high potential for endogenous self-repair. However, due to population aging,
human diseases with impaired bone regeneration are on the rise. Current strategies to …

Several publications have shown the phenomenon of osteoinduction by biomaterials to be
real. However, whether the ability of a biomaterial to initiate bone formation in ectopic …

Abstract Introduction OsteoFlux®(OF) is a 3D printed porous block of layered strands of
tricalcium phosphate (TCP) and hydroxyapatite. Its porosity and interconnectivity are …

Carbon nanotubes (CNTs) have been shown to affect cell behavior. But how and why the
CNTs affect potential differentiation of the attached cells has not been largely known. In this …