Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19

HM Al-Kuraishy, AI Al-Gareeb… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causative virus in the
development of coronavirus disease 2019 (Covid-19) pandemic. Respiratory manifestations …

Peroxisome proliferator-activated receptor-targeted therapies: Challenges upon infectious diseases

IS Kim, P Silwal, EK Jo - Cells, 2023 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) α, β, and γ are nuclear receptors that
orchestrate the transcriptional regulation of genes involved in a variety of biological …

Interplay of opposing effects of the WNT/β-catenin pathway and PPARγ and implications for SARS-CoV2 treatment

A Vallee, Y Lecarpentier, JN Vallee - Frontiers in immunology, 2021 - frontiersin.org
The Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2
(severe acute respiratory syndrome coronavirus 2), has quickly reached pandemic …

SARS-CoV-2 disease adjuvant therapies and supplements breakthrough for the infection prevention

AD Inchingolo, AM Inchingolo, IR Bordea, G Malcangi… - Microorganisms, 2021 - mdpi.com
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral
agent involved in the recent pandemic stated worldwide by the World Health Organization …

COVID‐19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advances

M Belchior‐Bezerra, RS Lima, NI Medeiros… - Obesity …, 2022 - Wiley Online Library
In the 2 years since the COVID‐19 pandemic was officially declared, science has made
considerable strides in understanding the disease's pathophysiology, pharmacological …

The 15-Months Clinical Experience of SARS-CoV-2: A Literature Review of Therapies and Adjuvants

AD Inchingolo, G Dipalma, AM Inchingolo, G Malcangi… - Antioxidants, 2021 - mdpi.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus
responsible for the coronavirus disease of 2019 (COVID-19) that emerged in December …

The role of peroxisome proliferator-activated receptors in the modulation of hyperinflammation induced by SARS-CoV-2 infection: A perspective for COVID-19 therapy

A Hasankhani, A Bahrami, B Tavakoli-Far… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a severe respiratory disease caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the lower …

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

VS Lekshmi, K Asha, M Sanicas, A Asi… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence and re-emergence of viral diseases, which cause significant global mortality
and morbidity, are the major concerns of this decade. Of these, current research is focused …

PPAR ligands induce antiviral effects targeting perturbed lipid metabolism during SARS-CoV-2, HCV, and HCMV infection

M Fantacuzzi, R Amoroso, A Ammazzalorso - Biology, 2022 - mdpi.com
Simple Summary The current coronavirus disease 2019 pandemic turned the attention of
researchers to developing novel strategies to counteract virus infections. Despite several …

An investigation for the interaction of gamma oryzanol with the Mpro of SARS-CoV-2 to combat COVID-19: DFT, molecular docking, ADME and molecular dynamics …

APS Raman, MB Singh, VK Vishvakarma… - Journal of …, 2023 - Taylor & Francis
COVID-19 has affected more or less every nation across the world and affected the economy
very badly. Infection of this virus in human took the life of millions. We have already faced the …