Association between antibiotics and gut microbiome dysbiosis in children: systematic review and meta-analysis
L McDonnell, A Gilkes, M Ashworth, V Rowland… - Gut …, 2021 - Taylor & Francis
Antibiotics in childhood have been linked with diseases including asthma, juvenile arthritis,
type 1 diabetes, Crohn's disease and mental illness. The underlying mechanisms are …
type 1 diabetes, Crohn's disease and mental illness. The underlying mechanisms are …
[HTML][HTML] Antibiotic exposure and adverse long-term health outcomes in children: a systematic review and meta-analysis
Background Antibiotics are amongst the most commonly used drugs in children. In addition
to inducing antibiotic resistance, antibiotic exposure has been associated with adverse long …
to inducing antibiotic resistance, antibiotic exposure has been associated with adverse long …
Gut microbiota diversity and human diseases: should we reintroduce key predators in our ecosystem?
Most of the Human diseases affecting westernized countries are associated with dysbiosis
and loss of microbial diversity in the gut microbiota. The Western way of life, with a wide use …
and loss of microbial diversity in the gut microbiota. The Western way of life, with a wide use …
Short-course antimicrobial therapy for pediatric community-acquired pneumonia: the SAFER randomized clinical trial
Importance Community-acquired pneumonia (CAP) is a common occurrence in childhood;
consequently, evidence-based recommendations for its treatment are required. Objective To …
consequently, evidence-based recommendations for its treatment are required. Objective To …
Biological classification of childhood arthritis: roadmap to a molecular nomenclature
Chronic inflammatory arthritis in childhood is heterogeneous in presentation and course.
Most forms exhibit clinical and genetic similarity to arthritis of adult onset, although at least …
Most forms exhibit clinical and genetic similarity to arthritis of adult onset, although at least …
Gut microbiome and autoimmune disorders
WA Shaheen, MN Quraishi… - Clinical and Experimental …, 2022 - academic.oup.com
Autoimmune diseases have long been known to share a common pathogenesis involving a
dysregulated immune system with a failure to recognize self from non-self-antigens. This …
dysregulated immune system with a failure to recognize self from non-self-antigens. This …
Administration of antibiotics to children before age 2 years increases risk for childhood obesity
Background & Aims Childhood obesity is increasing and is associated with adult obesity.
Antibiotics have been used to promote weight gain in livestock for several decades …
Antibiotics have been used to promote weight gain in livestock for several decades …
The long-term consequences of antibiotic therapy: Role of colonic short-chain fatty acids (SCFA) system and intestinal barrier integrity
Y Holota, T Dovbynchuk, I Kaji, I Vareniuk… - PLoS …, 2019 - journals.plos.org
Epidemiological studies revealed that antibiotics exposure increases a risk of inflammatory
bowel diseases (IBD) development. It remained largely unknown how antibiotic-induced …
bowel diseases (IBD) development. It remained largely unknown how antibiotic-induced …
A clinical update on the significance of the gut microbiota in systemic autoimmunity
EC Rosser, C Mauri - Journal of autoimmunity, 2016 - Elsevier
Systemic lupus erythematosus (SLE) is a complex autoimmune disease where a loss of
tolerance to nuclear antigens leads to inflammation in multiple organ systems. The cause of …
tolerance to nuclear antigens leads to inflammation in multiple organ systems. The cause of …
Advances in optimizing the prescription of antibiotics in outpatient settings
LM King, KE Fleming-Dutra, LA Hicks - Bmj, 2018 - bmj.com
The inappropriate use of antibiotics can increase the likelihood of antibiotic resistance and
adverse events. In the United States, nearly a third of antibiotic prescriptions in outpatient …
adverse events. In the United States, nearly a third of antibiotic prescriptions in outpatient …