Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation,
and survival of sympathetic and sensory afferent neurons during development. A substantial …

There is growing interest in the complex relationship between the nervous and immune
systems and how its alteration can affect homeostasis and result in the development of …

The urothelium, which lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, not only forms a high-resistance barrier to ion, solute and water flux, and …

Traumatic spinal cord injury (SCI) has widespread physiological effects beyond the
disruption of sensory and motor function, notably the loss of normal autonomic and …

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Chronic pain continues to be a significant global burden despite the availability of a variety
of nonpharmacologic and pharmacologic treatment options. Thus, there is a need for new …

Spinal cord injury (SCI) damages multiple structures at the lesion site, including ascending,
descending, and propriospinal axons; interrupting the conduction of information up and …

Clinical guidelines for interstitial cystitis and hypersensitive bladder have been updated as
of 2015. The guidelines define interstitial cystitis by the presence of hypersensitive bladder …

In the last two decades, nerve growth factor (NGF), initially described as a prototypical
trophic factor in the development of sensory and sympathetic innervation, has emerged as a …