The oligometastatic spectrum in the era of improved detection and modern systemic therapy

RR Katipally, SP Pitroda, A Juloori… - Nature Reviews …, 2022 - nature.com
Metastases remain the leading cause of cancer-related mortality. The oligometastasis
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …

Emerging evidence and treatment paradigm of non-small cell lung cancer

SYM Liu, MM Zheng, Y Pan, SY Liu, Y Li… - Journal of hematology & …, 2023 - Springer
Research on biomarker-driven therapy and immune check-point blockade in non-small cell
lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical trials have also …

Systemic and oligo-acquired resistance to PD-(L) 1 blockade in lung cancer

AJ Schoenfeld, HA Rizvi, D Memon, N Shaverdian… - Clinical Cancer …, 2022 - AACR
Purpose: Clinical patterns and the associated optimal management of acquired resistance to
PD-(L) 1 blockade are poorly understood. Experimental Design: All cases of metastatic lung …

Oligometastasis in breast cancer—current status and treatment options from a radiation oncology perspective

MD Piroth, D Krug, P Feyer, R Baumann… - Strahlentherapie und …, 2022 - Springer
Evidence from a few small randomized trials and retrospective cohorts mostly including
various tumor entities indicates a prolongation of disease free survival (DFS) and overall …

Optimize Local Therapy for Oligometastatic and Oligoprogressive Non–Small Cell Lung Cancer to Enhance Survival

JY Chang, V Verma - Journal of the National Comprehensive Cancer …, 2022 - jnccn.org
Metastatic non–small cell lung cancer (NSCLC) is highly heterogeneous, and there are
patients with limited areas of metastases (oligometastases) or progression …

Local consolidative therapy versus systemic therapy alone for metastatic non-small cell lung cancer: a systematic review and meta-analysis

Y Wu, V Verma, F Liang, Q Lin, Z Zhou, Z Wang… - International Journal of …, 2022 - Elsevier
Purpose The role of local consolidative therapy (LCT) for metastatic cancers most likely
varies by the particular cancer type. We therefore performed a systematic review with a …

Stereotactic body radiation therapy in patients with oligometastatic disease: Clinical state of the art and perspectives

R Kinj, E Muggeo, L Schiappacasse, J Bourhis… - Cancers, 2022 - mdpi.com
Simple Summary Stereotactic radiation therapy (SBRT) is a type of radiation therapy in
which a small number of high doses of radiation are delivered to a target volume using …

[HTML][HTML] Oligoprogression in non-small cell lung cancer: a narrative review

KT Nguyen, G Sakthivel, MT Milano, H Qiu… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Oligoprogression in non-small cell lung cancer: a narrative review - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

Oligoprogression of solid tumors on immune checkpoint inhibitors: the impact of local ablative radiation therapy

KK Sindhu, AD Nehlsen, EJ Lehrer, JP Rowley… - Biomedicines, 2022 - mdpi.com
The breakthrough of a limited number of clones while on immune checkpoint inhibitors
(ICIs), known as oligoprogression, has been previously described. The benefit of ablative …

Outcomes for oligometastatic head and neck cancer treated with stereotactic body radiotherapy: Results from an international multi‐institutional consortium

B Id Said, A Mutsaers, H Chen, ZA Husain… - Head & …, 2023 - Wiley Online Library
Background We report the results of an international multi‐institutional cohort of
oligometastatic (OMD) head and neck cancer (HNC) patients treated with SBRT. Methods …