Environmental factors in declining human fertility

NE Skakkebæk, R Lindahl-Jacobsen… - Nature Reviews …, 2022 - nature.com
A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Intrauterine growth restriction: postnatal monitoring and outcomes

K Kesavan, SU Devaskar - Pediatric Clinics, 2019 - pediatric.theclinics.com
Intrauterine growth restriction (IUGR) continues to be a challenging problem for clinicians
despite advances in both obstetric and neonatal care. IUGR is defined as a rate of fetal …

Endocrine‐disrupting chemicals: associated disorders and mechanisms of action

S De Coster, N Van Larebeke - Journal of environmental and …, 2012 - Wiley Online Library
The incidence and/or prevalence of health problems associated with endocrine‐disruption
have increased. Many chemicals have endocrine‐disrupting properties, including bisphenol …

Ultrasound of the male genital tract in relation to male reproductive health

F Lotti, M Maggi - Human reproduction update, 2015 - academic.oup.com
BACKGROUND Infertility affects∼ 7% of all men. Despite much progress, mainly in
genetics, its etiology remains obscure in∼ 50% of cases. To fill this gap, imaging of the male …

Semen quality in the 21st century

HE Virtanen, N Jørgensen, J Toppari - Nature Reviews Urology, 2017 - nature.com
Although semen quality is an important determinant of fertility, defining clear thresholds for
normal ranges has proven difficult. According to'time to pregnancy'studies, fecundity starts to …

Environmental/lifestyle effects on spermatogenesis

RM Sharpe - … Transactions of the Royal Society B …, 2010 - royalsocietypublishing.org
The high incidence of low sperm counts in young (European) men and evidence for
declining sperm counts in recent decades mean that the environmental/lifestyle impact on …

Small for gestational age: short stature and beyond

P Saenger, P Czernichow, I Hughes… - Endocrine …, 2007 - academic.oup.com
Depending on the definitions used, up to 10% of all live-born neonates are small for
gestational age (SGA). Although the vast majority of these children show catch-up growth by …

Environmental factors, epigenetics, and developmental origin of reproductive disorders

SM Ho, A Cheong, MA Adgent, J Veevers… - Reproductive …, 2017 - Elsevier
Sex-specific differentiation, development, and function of the reproductive system are largely
dependent on steroid hormones. For this reason, developmental exposure to estrogenic and …

Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men

N Jørgensen, UN Joensen, TK Jensen, MB Jensen… - BMJ open, 2012 - bmjopen.bmj.com
Objectives Considerable interest and controversy over a possible decline in semen quality
during the 20th century raised concern that semen quality could have reached a critically …