Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

SC Dyall, L Balas, NG Bazan, JT Brenna… - Progress in lipid …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology

S Laye, A Nadjar, C Joffre, RP Bazinet… - Pharmacological …, 2018 - Elsevier
Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

N Chiang, S Libreros, PC Norris… - The Journal of …, 2023 - Am Soc Clin Investig
Resolution of acute inflammation is an active process orchestrated by endogenous
mediators and mechanisms pivotal in host defense and homeostasis. The macrophage …

EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid …

J So, D Wu, AH Lichtenstein, AK Tai, NR Matthan… - Atherosclerosis, 2021 - Elsevier
Background and aims The independent effects of eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid …

Mass spectrometry‐based lipidomics in food science and nutritional health: A comprehensive review

T Sun, X Wang, P Cong, J Xu… - … Reviews in Food Science …, 2020 - Wiley Online Library
With the advance in science and technology as well as the improvement of living standards,
the function of food is no longer just to meet the needs of survival. Food science and its …

The n-3 docosapentaenoic acid (DPA): A new player in the n-3 long chain polyunsaturated fatty acid family

G Drouin, V Rioux, P Legrand - Biochimie, 2019 - Elsevier
The n-3 docosapentaenoic acid (n-3 DPA) is less studied n-3 long-chain polyunsaturated
fatty acid (LCPUFA), compared to its counterparts eicosapentaenoic acid (EPA) and …

[HTML][HTML] Exercise immunology: future directions

DC Nieman, BD Pence - Journal of Sport and Health Science, 2020 - Elsevier
Several decades of research in the area of exercise immunology have shown that the
immune system is highly responsive to acute and chronic exercise training. Moderate …

Narrative Review of n-3 Polyunsaturated Fatty Acid Supplementation upon Immune Functions, Resolution Molecules and Lipid Peroxidation

GP Zaloga - Nutrients, 2021 - mdpi.com
Fish oil supplementation is commonplace in human nutrition and is being used in both
enteral and parenteral formulations during the treatment of patients with a large variety of …

Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology

J Dalli, CN Serhan - British journal of pharmacology, 2019 - Wiley Online Library
Inflammatory diseases are a major socio‐economic burden, with the incidence of such
conditions on the rise, especially in western societies. For decades, the primary treatment …