Bartonella species, an emerging cause of blood-culture-negative endocarditis

U Okaro, A Addisu, B Casanas… - Clinical Microbiology …, 2017 - Am Soc Microbiol
Since the reclassification of the genus Bartonella in 1993, the number of species has grown
from 1 to 45 currently designated members. Likewise, the association of different Bartonella …

Intruders below the radar: molecular pathogenesis of Bartonella spp

A Harms, C Dehio - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Bartonella spp. are facultative intracellular pathogens that employ a unique stealth infection
strategy comprising immune evasion and modulation, intimate interaction with nucleated …

Bacterial Type IV secretion systems: versatile virulence machines

DE Voth, LJ Broederdorf, JG Graham - Future microbiology, 2012 - Taylor & Francis
Many bacterial pathogens employ multicomponent protein complexes to deliver
macromolecules directly into their eukaryotic host cell to promote infection. Some Gram …

Breaking the wall: targeting of the endothelium by pathogenic bacteria

E Lemichez, M Lecuit, X Nassif… - Nature Reviews …, 2010 - nature.com
The endothelium lining blood and lymphatic vessels is a key barrier separating body fluids
from host tissues and is a major target of pathogenic bacteria. Endothelial cells are actively …

Oroya fever and verruga peruana: bartonelloses unique to South America

MF Minnick, BE Anderson, A Lima… - PLoS neglected …, 2014 - journals.plos.org
Bartonella bacilliformis is the bacterial agent of Carrión's disease and is presumed to be
transmitted between humans by phlebotomine sand flies. Carrión's disease is endemic to …

Bartonella spp.: throwing light on uncommon human infections

PO Kaiser, T Riess, F O'Rourke, D Linke… - International Journal of …, 2011 - Elsevier
After 2 decades of Bartonella research, knowledge on transmission and pathology of these
bacteria is still limited. Bartonella spp. have emerged to be important pathogens in human …

Embedded spheroids as models of the cancer microenvironment

KM Tevis, YL Colson, MW Grinstaff - Advanced biosystems, 2017 - Wiley Online Library
To more accurately study the complex mechanisms behind cancer invasion, progression,
and response to treatment, researchers require models that replicate both the multicellular …

Persistence of Bartonella spp. stealth pathogens: from subclinical infections to vasoproliferative tumor formation

AT Pulliainen, C Dehio - FEMS microbiology reviews, 2012 - academic.oup.com
Bartonella spp. are facultative intracellular bacteria that typically cause a long-lasting
intraerythrocytic bacteremia in their mammalian reservoir hosts, thereby favoring …

Parallel Evolution of a Type IV Secretion System in Radiating Lineages of the Host-Restricted Bacterial Pathogen Bartonella

P Engel, W Salzburger, M Liesch, CC Chang… - PLoS …, 2011 - journals.plos.org
Adaptive radiation is the rapid origination of multiple species from a single ancestor as the
result of concurrent adaptation to disparate environments. This fundamental evolutionary …

Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins

Y Rikihisa, M Lin - Current opinion in microbiology, 2010 - Elsevier
The obligatory intracellular bacterial pathogens Anaplasma and Ehrlichia infect leukocytes
by hijacking host-cell components and processes. The type IV secretion system is up …