Four decades after the discovery of regenerating islet-derived (Reg) proteins: current understanding and challenges
Z Chen, S Downing, ES Tzanakakis - Frontiers in cell and …, 2019 - frontiersin.org
Regenerating islet-derived (Reg) proteins have emerged as multifunctional agents with pro-
proliferative, anti-apoptotic, differentiation-inducing and bactericidal properties. Over the last …
proliferative, anti-apoptotic, differentiation-inducing and bactericidal properties. Over the last …
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR−/−) mouse
EO List, L Sackmann-Sala, DE Berryman… - Endocrine …, 2011 - academic.oup.com
Disruption of the GH receptor (GHR) gene eliminates GH-induced intracellular signaling
and, thus, its biological actions. Therefore, the GHR gene disrupted mouse (GHR−/−) has …
and, thus, its biological actions. Therefore, the GHR gene disrupted mouse (GHR−/−) has …
[HTML][HTML] High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and β-cell apoptosis
Z Zhang, CW Liew, DE Handy, Y Zhang… - The FASEB …, 2010 - ncbi.nlm.nih.gov
Patients with type 2 diabetes lose β cells, but the underlying mechanisms are incompletely
understood. Glucose-6-phosphate dehydrogenase (G6PD) is the principal source of the …
understood. Glucose-6-phosphate dehydrogenase (G6PD) is the principal source of the …
The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach
H Lu, Y Yang, EM Allister, N Wijesekara… - Molecular & Cellular …, 2008 - ASBMB
Type 2 diabetes (T2D) arises when pancreatic β-cells fail to compensate for systemic insulin
resistance with appropriate insulin secretion. However, the link between insulin resistance …
resistance with appropriate insulin secretion. However, the link between insulin resistance …
Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis
Diabetes mellitus (DM) is considered a global pandemic, and the incidence of DM continues
to grow worldwide. Nutrients and dietary patterns are central issues in the prevention …
to grow worldwide. Nutrients and dietary patterns are central issues in the prevention …
Gene-diet interactions in type 2 diabetes: the chicken and egg debate
Consistent evidence from both experimental and human studies indicates that Type 2
diabetes mellitus (T2DM) is a complex disease resulting from the interaction of genetic …
diabetes mellitus (T2DM) is a complex disease resulting from the interaction of genetic …
Geraniin protects high-fat diet-induced oxidative stress in Sprague Dawley rats
APYS Chung, S Gurtu, S Chakravarthi, M Moorthy… - Frontiers in …, 2018 - frontiersin.org
Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has
been shown to possess significant antioxidant activity in vitro and recently been recognized …
been shown to possess significant antioxidant activity in vitro and recently been recognized …
Molecular pathways and nutrigenomic review of insulin resistance development in gestational diabetes mellitus
P Guevara-Ramírez, E Paz-Cruz… - Frontiers in …, 2023 - frontiersin.org
Gestational diabetes mellitus is a condition marked by raised blood sugar levels and insulin
resistance that usually occurs during the second or third trimester of pregnancy. According to …
resistance that usually occurs during the second or third trimester of pregnancy. According to …
[HTML][HTML] High fat diet regulation of β-cell proliferation and β-cell mass
ML Golson, AA Misfeldt, UG Kopsombut… - The open …, 2010 - ncbi.nlm.nih.gov
Abstract Type 2 Diabetes (T2D) is characterized by relative insulin insufficiency, caused
when peripheral tissues such as liver, muscle, and adipocytes have a decreased response …
when peripheral tissues such as liver, muscle, and adipocytes have a decreased response …
In vitro and in vivo safety assessment of edible blue-green algae, Nostoc commune var. sphaeroides Kützing and Spirulina plantensis
Blue-green algae (BGA) have been consumed as food and herbal medicine for centuries.
However, safety for their consumption has not been well investigated. This study was …
However, safety for their consumption has not been well investigated. This study was …