Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li,-Mg and-Zn reagents

V Dhayalan, VS Dodke, MP Kumar… - Chemical Society …, 2024 - pubs.rsc.org
This review highlights the use of functionalized organo-Li,-Mg and-Zn reagents for the
construction and selective functionalization of 5-and 6-membered fused bicyclic …

Dihydroazolopyrimidines: Past, Present and Perspectives in Synthesis, Green Chemistry and Drug Discovery

SM Desenko, MY Gorobets, VV Lipson… - The Chemical …, 2024 - Wiley Online Library
Dihydroazolopyrimidines are an important class of heterocycles that are isosteric to natural
purines and are therefore of great interest primarily as drug‐like molecules. In contrast to the …

Calculation-assisted regioselective functionalization of the imidazo [1, 2-a] pyrazine scaffold via zinc and magnesium organometallic intermediates

A Kastrati, A Kremsmair, AS Sunagatullina… - Chemical …, 2023 - pubs.rsc.org
Straightforward calculations such as determinations of pKa values and N-basicities have
allowed the development of a set of organometallic reactions for the regioselective …

Transition‐Metal Free Electrophilic Aminations of Polyfunctional O‐2,4,6‐Trimethylbenzoyl Hydroxylamines with Zinc and Magnesium Organometallics

AS Sunagatullina, A Hess, A Kremsmair… - Angewandte Chemie …, 2023 - Wiley Online Library
We reported a new electrophilic amination of various primary, secondary and tertiary alkyl,
benzylic, allylic zinc and magnesium organometallics with O‐2, 4, 6‐trimethylbenzoyl …

[HTML][HTML] Properties of AlCl3 guanidine deep eutectic solvent with addition of polyethylene oxide of different molecular weights supported by quantum-chemical …

R Tangalychev, V Korotenko, I Efimov… - Journal of Energy …, 2024 - Elsevier
Deep eutectic solvent of AlCl 3 with guanidine HCl was synthesized in the molar ratio 3: 1 in
the presence of polyethylene glycols of various molecular weights from 1500 to 5· 10 6 …

Recent advances in the chemistry of pyrazolo [1, 5-a] pyrimidines

J Portilla - Advances in Heterocyclic Chemistry, 2024 - books.google.com
Recent advances in the chemistry of pyrazolo [1, 5-a] pyrimidines Page 82 CHAPTER TWO
Recent advances in the chemistry of pyrazolo [1, 5- a ] pyrimidines Jaime Portilla * Bioorganic …

Übergangsmetallfreie elektrophile Aminierungen von polyfunktionellen O‐2, 4, 6‐Trimethylbenzoylhydroxylaminen mit Zink‐und Magnesiumorganometallen

AS Sunagatullina, A Hess, A Kremsmair… - Angewandte …, 2023 - Wiley Online Library
Wir berichteten über eine neue elektrophile Aminierung verschiedener primärer, sekundärer
und tertiärer Alkyl‐, Benzyl‐, Allylzink‐und Magnesiumorganometalle mit O‐2, 4, 6 …

Regioselective Annulation of 3(5)‐Aminopyrazole with Aryl Ketones or Aryl Alkynes Using N,N‐Dimethylethanolamine as a Single/Triple Carbon Synthon

X Zhang, J Chen, R Chen, L Wang… - Advanced Synthesis & … - Wiley Online Library
An efficient and regioselective cyclization for construction of pyrazolo [3, 4‐b] pyridines and
methylene‐bridged bis (pyrazolo [1, 5‐a] pyrimidines) has been established. It involves a [3+ …

Expeditious Robust Elaboration of Bicyclic N-Heterocycles

P Richardson - Synfacts, 2022 - thieme-connect.com
Significance: The ability to predictably functionalize novel heterocyclic cores enables
researchers to access unexplored chemical space in the discovery and development of …

Five-membered ring systems: with more than one N atom

L Yet - Progress in Heterocyclic Chemistry, 2024 - Elsevier
Five-membered ring systems: with more than one N atom - ScienceDirect Skip to main
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